Year 2017 / Volume 109 / Number 11
Original
Colonic diverticulosis and the metabolic syndrome: an association?

768-771

DOI: 10.17235/reed.2017.5009/2017

Cristina Teixeira, Daniel Trabulo, Suzane Ribeiro, Cláudio Rodrigues Martins, Ana Luísa Alves, Isabelle Cremers, Ana Paula Oliveira,

Abstract
Background and objectives: Colonic diverticulosis (CD) is related to advanced age and a lack of dietary fiber. Recently, several studies have shown that metabolic syndrome (MS) is also implicated in the etiopathogenesis of CD. This study aimed to assess the association between MS, obesity and CD. Methods: This was a prospective study of a one-year duration. The MS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III). Demographic data, risk factors for MS and endoscopic findings of patients who underwent a total colonoscopy in the department were collected. Obesity was defined as a body mass index ≥ 30 kg/m2. Informed consent was obtained. The local Ethics Committee and National Data Protection Committee approved the study. Statistical analysis was performed with SPSS 21 and statistical significance was defined as p < 0.05. Results: The study included 203 patients, 95 males with a mean age of 65.5 years. CD was diagnosed in 30.5% of patients. Univariate analysis showed that age, hypertension, increased waist circumference and hyperlipidemia were associated with colonic diverticulosis. There was no association with gender, obesity or type 2 diabetes mellitus. Multivariate analysis showed that age and a greater waist circumference increased the risk of diverticulosis. Age-adjusted analysis showed that MS was associated with diverticulosis. The prevalence of adenoma in patients with CD was similar to that in patients without CD. Conclusion: In this series, MS was significantly associated with CD. The identification of risk groups is important since diverticulosis can have serious and potentially fatal complications. To our knowledge, this is the first Southern European prospective study evaluating the association between MS and CD.
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02/12/2017 5:43:28
Interesante artículo de correlación. La pregunta estaría en relación a qué tanto puede influir solo el perímetro abdominal mayor de 88 o 102 cm según sexo?


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Publication history

Received: 13/04/2017

Accepted: 14/07/2017

Online First: 04/08/2017

Published: 02/11/2017

Article revision time: 87 days

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