Year 2025 / Volume 117 / Number 7
Letter
Acute hepatitis secondary to febuxostat

414-415

DOI: 10.17235/reed.2023.10047/2023

Miryam Moreta Rodríguez, Carlos Maroto Martin, Frank Suárez López, Javier Miguel Martín Guerra,

Abstract
Febuxostat is a drug from the group of xanthine dehydrogenase inhibitors and is used in the treatment of hyperuricemia and gouty arthritis. However, it is not free of adverse effects, including alteration of liver profile tests. This is why we must pay attention to this type of adverse events in case it is necessary to suspend treatment. We present a clinical case of acute hepatitis secondary to Febuxostat.
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References
1. Ichida K. [New antihyperuricemic medicine: febuxostat, Puricase, etc]. Nihon Rinsho. 2008 Apr;66(4):759-65. Japanese. PMID: 18409528.
2. Ficha técnica de Febuxostat. Disponible en : https://cima.aemps.es/cima/dochtml/p/83626/P_83626.html4
3. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30:239-45.
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Moreta Rodríguez M, Maroto Martin C, Suárez López F, Martín Guerra J. Acute hepatitis secondary to febuxostat. 10047/2023


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Publication history

Received: 29/10/2023

Accepted: 04/11/2023

Online First: 20/11/2023

Published: 08/07/2025

Article Online First time: 22 days

Article editing time: 618 days


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