Year 2009 / Volume 101 / Number 7
Original
Onset and disappearance rates of gastroesophageal reflux symptoms in the Spanish population, and their impact on quality of life

pp. 477-482

Rey, E. / Álvarez-Sánchez, A. / Rodríguez-Artalejo, F. / Moreno Elola-Olaso, C. / Almansa, C. / Díaz-Rubio, M.

Abstract
Background: few studies have reported the onset and disappearance rates of gastroesophageal reflux symptoms (GERS) in the population.
Aim: to assess the occurrence and disappearance rates of GERS in Spain, and their impact on health-related quality of life (HRQL).
Participants and methods: participants were selected at random from the general population of Madrid in age and sex strata. They were interviewed at home twice, 6 months apart. Heartburn, acid regurgitation and consultation were assessed with the gastroesophageal reflux questionnaire, and HRQL with the SF-36.
Results: 709 individuals were included, and 451 (63.6%) were re-interviewed 6 months later. Among the 325 individuals without GERS, 9 developed weekly symptoms (2.2% [95% CI: 0.8, 3.4%]); 2 (22%) consulted because of GERS. Among the 34 subjects reporting weekly GERS initially, 26 did not report them at 6-months. Onset of GERS was associated with worsening scores in the physical summary of SF-36 (delta = -6.6 [95% CI: -11.8, -1.42]), while disappearance with an improved score (delta = -3.0 [95% CI: 0.0, 5.9]).
Conclusion: despite the lower prevalence of GERS in Spain, the occurrence rate is 2.2% in 6 months; however symptoms disappeared in more than half of subjects six months later. Developing GERS was associated with reduced HRQL, and their disappearance with improvement.
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Rey, E. / Álvarez-Sánchez, A. / Rodríguez-Artalejo, F. / Moreno Elola-Olaso, C. / Almansa, C. / Díaz-Rubio, M.. Onset and disappearance rates of gastroesophageal reflux symptoms in the Spanish population, and their impact on quality of life. 477-482


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