Year 2025 / Volume 117 / Number 12
Letter
Association between ulcerative colitis and acute appendicitis - A Mendelian randomization study

794-795

DOI: 10.17235/reed.2024.10818/2024

Sangsang Chen, Zhebin Dong, Hanting Xiang, Chao Liang,

Abstract
Although the etiology of UC is not clear, some studies show that the appendix may be the starting point of UC, and the incidence of appendicitis is high in patients with UC. We performed a MR analysis to examine whether there is a potential causal relationship between UC and acute appendicitis. Our MR study revealed that the genetic liability of UC (OR, 0.9362; 95% CI 0.9014 – 0.9723; p = 0.00064) was associated with a decreased risk of acute appendicitis. More research is needed in the future to support our findings and better explain why UC reduces the risk of acute appendicitis.
New comment
Comments
No comments for this article
Related articles

Letter

Brief description of Mendelian randomized studies

DOI: 10.17235/reed.2024.10917/2024

Letter

Broadening perspectives in the treatment of chronic pouchitis

DOI: 10.17235/reed.2024.10865/2024

Letter

Ulcerative colitis complicated with hypermucinous dysplasia

DOI: 10.17235/reed.2024.10348/2024

Letter

Diffuse colonic capillary hemangioma mimicking ulcerative colitis

DOI: 10.17235/reed.2024.10298/2024

Letter

Tofacitinib-induced eosinophilia

DOI: 10.17235/reed.2023.9831/2023

Letter

Perianal Paget’s disease

DOI: 10.17235/reed.2022.9304/2022

Letter

Chinese dragon sign of ulcerative colitis

DOI: 10.17235/reed.2022.9154/2022

Letter

Schwannoma of the ileocecum accompanied by acute appendicitis

DOI: 10.17235/reed.2022.9053/2022

Letter

Ulcerative colitis exacerbated by strongyloidiasis

DOI: 10.17235/reed.2022.9044/2022

Review

Clinical settings with tofacitinib in ulcerative colitis

DOI: 10.17235/reed.2022.8660/2022

Letter

Mesalazine induced interstitial pneumonitis in the COVID era

DOI: 10.17235/reed.2022.8635/2021

Letter

The effect of Adacolumn® on ulcerative colitis with COVID-19

DOI: 10.17235/reed.2020.7156/2020

Letter

Sweet syndrome in severe ulcerative flare

DOI: 10.17235/reed.2020.6995/2020

Letter to the Editor

Acute appendicitis after a colonic endoscopic submucosal resection

DOI: 10.17235/reed.2018.5307/2017

Letter to the Editor

Ulcerative colitis with gastric and duodenal involvement

DOI: 10.17235/reed.2017.4685/2016

Editorial

Specialist care in the management of inflammatory bowel disease

DOI: 10.17235/reed.2016.4628/2016

Original

Mercaptopurine and inflammatory bowel disease: the other thiopurine

DOI: 10.17235/reed.2016.4546/2016

Case Report

Mesalamine-induced myopericarditis - A case report

DOI: 10.17235/reed.2016.4016/2015

Citation tools
Chen S, Dong Z, Xiang H, Liang C. Association between ulcerative colitis and acute appendicitis - A Mendelian randomization study. 10818/2024


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 7 visits.
This article has been downloaded 0 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 24/09/2024

Accepted: 09/10/2024

Online First: 18/10/2024

Published: 12/12/2025

Article Online First time: 24 days

Article editing time: 444 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2025 y Creative Commons. The Spanish Journal of Gastroenterology