Year 2023 / Volume 115 / Number 10
Digestive Diseases Image
Severe gastritis in a patient treated with immunotherapy: immune-mediated or reactivation of cytomegalovirus?

578-579

DOI: 10.17235/reed.2022.9158/2022

Sonia Rebeca Vallejo Rivera, Lidia Nicolás Niza, Lucía Bonilla López, Juan Díaz Concepción,

Abstract
Cancer patients receiving programmed death 1 (PD-1) immune checkpoint blockade therapy are susceptible, due to immunosuppression, to a variety of infections including cytomegalovirus infection. We report an unusual case of histologically confirmed gastritis due to cytomegalovirus infection in a patient who had metastatic melanoma and received PD-1 blockade therapy with pembrolizumab. Pembrolizumab was discontinued and treatment with intravenous ganciclovir and oral vangaciclovir was initiated; the patient's symptoms improved significantly.
Share Button
New comment
Comments
No comments for this article
References
Lu J, Firpi-Morell RJ, Dang LH, et al. An Unusual Case of Gastritis in One Patient Receiving PD-1 Blocking Therapy: Coexisting Immune-Related Gastritis and Cytomegaloviral Infection. Gastroenterol Res. 2018;11:383–7.
Hulo P, Touchefeu Y, Cauchin E, et al. Acute Ulceronecrotic Gastritis With Cytomegalovirus Reactivation: Uncommon Toxicity of Immune Checkpoint Inhibitors in Microsatellite Instability–High Metastatic Colorectal Cancer. Clin Colorectal Cancer. 2020;19:e183–8.
Ojeda Gómez A, Jiménez García N, Barragán Martínez J, et al. Acute neutrophilic gastritis induced by nivolumab used as treatment for non- metastatic malignant melanoma. Rev Esp Enferm Dig. 2021 Dec;113(12):853-854.
Related articles

Letter

Sepsis due to phlegmonous gastritis in a cancer patient

DOI: 10.17235/reed.2022.9009/2022

Digestive Diseases Image

An unusual cause of a protuberant lesion of the gastric antrum

DOI: 10.17235/reed.2022.8771/2022

Letter

Ischemic gastritis and severe diabetic ketoacidosis

DOI: 10.17235/reed.2020.7655/2020

Letter

Luetic gastritis: an uncommon cause of gastritis

DOI: 10.17235/reed.2020.6870/2020

Letter

Ischemic gastritis due to oral iron

DOI: 10.17235/reed.2019.6401/2019

Case Report

Emphysematous esophagitis with gastric perforation

DOI: 10.17235/reed.2019.6322/2019

Letter to the Editor

Cytomegalovirus: associated ischemic colitis in an immunocompetent patient

DOI: 10.17235/reed.2017.4937/2017

Case Report

Gastric varicella: two cases in cancer patients

DOI: 10.17235/reed.2016.3925/2015

Citation tools
Vallejo Rivera S, Nicolás Niza L, Bonilla López L, Díaz Concepción J. Severe gastritis in a patient treated with immunotherapy: immune-mediated or reactivation of cytomegalovirus? . 9158/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 351 visits.
This article has been downloaded 72 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 26/08/2022

Accepted: 14/09/2022

Online First: 07/10/2022

Published: 09/10/2023

Article Online First time: 42 days

Article editing time: 409 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology