Year 2008 / Volume 100 / Number 9
Original
Seropositivity to Helicobacter pylori among university students and their families. A comparative cross-sectional study

pp. 540-544

Guzmán-Domínguez, G. / Newton-Sánchez, O. A. / Bustos-Saldaña, R. / Guzmán-Villa, B. M. / Barajas-Martínez, A.

Abstract
Objective: to associate serologic response to Helicobacter pylori (Hp) among seropositive university students and their families in western Mexico.

Methods: we conducted a comparative transversal study, and randomized 30 nuclear families of 14 Hp-seropositive university students and 14 Hp-seronegative university students. We carried out seropositivity measurements (IgG) to Hp using the ELISA method. An analysis was performed utilizing the chi-squared and Mann-Whitney U tests, with the aid of EPI INFO 2000 and SIGMA STAT 3.2 software.

Results: global seropositivity in the families of infected students was 57 vs. 13% of the relatives of non-infected students (p = 0.000002). In families of Hp-positive students we found the following frequencies: parental (father and mother) 70%; mother 71%, and siblings 42%, while for seronegative individuals incidences were: parental 17% (p = 0.00005), mother 12% (p = 0.001), and siblings 10% (p = 0.0076).

Conclusions: there is a greater prevalence of antibodies againts Hp in the relatives of seropositive students.
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Guzmán-Domínguez, G. / Newton-Sánchez, O. A. / Bustos-Saldaña, R. / Guzmán-Villa, B. M. / Barajas-Martínez, A.. Seropositivity to Helicobacter pylori among university students and their families. A comparative cross-sectional study. 540-544


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