Year 2008 / Volume 100 / Number 6
Original
Effectiveness, safety, and tolerability of intragastric balloon in association with low-calorie diet for the treatment of obese patients

pp. 349-354

Escudero Sanchis, A. / Catalán Serra, I. / Gonzalvo Sorribes, J. / Bixquert Jiménez, M. / Navarro López, L. / Herrera García, L. / Durbán Serrano, L. / Monforte Albalat, A.

Abstract
Introduction: the endoscopic placement of an intragastric balloon (IGB) in association with a low-calorie diet is an option for the treatment of obesity. The aim of the present study was to evaluate its effectiveness, safety, and tolerance.

Material and methods: thirty-eight patients with no contraindications for IGB were included in this prospective study from March 2004 to January 2007. Balloon removal was performed 6 months later. Weight and body mass index (BMI) were evaluated after IGB removal and at 6 months and 1 year thereafter. Tolerance and complications during treatment were evaluated. Patients filled out a questionnaire to evaluate their subjective perception of treatment.

Results: mean weight loss after 6 months on balloon treatment was 14.10 kg (0-46), and mean BMI reduction was 5.23 kg/m2 (0-18). At 12 months after balloon removal 48.4% of patients maintained their weight loss or kept loosing weight. Most common early symptoms included nausea (71.1%) and vomiting (57.9%) with a good response to symptomatic treatment. Complications were seen in 7 patients (18.4%): digestive intolerance in 4 patients, with early removal in 3 of them; moderate esophagitis in 2 patients; and gastric perforation complicated with septic shock and death in 1 patient.

Conclusions:

1. IGB in association with low-calorie diet is an effective, safe, and well tolerated treatment for morbid obese patients.

2. Almost half of patients maintained their weight loss after one year from balloon removal.
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Escudero Sanchis, A. / Catalán Serra, I. / Gonzalvo Sorribes, J. / Bixquert Jiménez, M. / Navarro López, L. / Herrera García, L. / Durbán Serrano, L. / Monforte Albalat, A.. Effectiveness, safety, and tolerability of intragastric balloon in association with low-calorie diet for the treatment of obese patients. 349-354


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