Year 2023 / Volume 115 / Number 9
Letter
Diagnosis of a cystic pancreatic neuroendocrine tumor: is cystic fluid chromogranin A useful?

526-527

DOI: 10.17235/reed.2022.9366/2022

Eva Marín Serrano, Marta Duque Alcorta,

Abstract
Cystic pancreatic neuroendocrine tumors (cP-NET) are a diagnostic challenge for clinic, since sometimes nor imaging features, cytology, or the study of biological markers in pancreatic cyst fluid (PCF), are able to provide the nature of the lesion, and therefore the definitive diagnostic is often made in the surgical piece. Is not infrequent that the lesions are wrongly defined as benign, in special when the cytology is negative for malignancy and the PCL is not mucinous and has a high glucose and a low CEA. We could incorporate new markers to improve the diagnostic performance of PCF samples, like chromogranin A, as in our case may be the only specific finding to detect a cP-TNE.
Share Button
New comment
Comments
No comments for this article
References
Nakashima Y, Ohtsuka T, Nakamura S, et al. Clinicopathological characteristics of non-functioning cystic pancreatic neuroendocrine tumors. Pancreatology. 2019; 19(1): 50-56.
Sakorafas GH, Smyrniotis V, Reid-Lombardo KM, et al. Primary pancreatic cystic neoplasms of the pancreas revisited. Part IV: rare cystic neoplasms. Surg Oncol. 2012; 21(3):153-63.
Morales-Oyarvide V, Yoon WJ, Ingkakul T, et al. Cystic pancreatic neuroendocrine tumors: the value of cytology in preoperative diagnosis. Cancer Cytopathol. 2014; 122(6): 435-44.
Levy A, Popovici T, Bories PN. Tumor markers in pancreatic cystic fluids for diagnosis of malignant cysts. Int J Biol Markers. 2017; 32(3): e291-e296.
Faias S, Prazeres S, Cunha M, et al. Chromogranin A and NSE in cystic pancreatic neuroendocrine tumors. Clin Res Hepatol Gastroenterol. 2021; 45(4):101601.
Citation tools
Marín Serrano E, Duque Alcorta M. Diagnosis of a cystic pancreatic neuroendocrine tumor: is cystic fluid chromogranin A useful?. 9366/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 381 visits.
This article has been downloaded 69 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 16/11/2022

Accepted: 22/11/2022

Online First: 01/12/2022

Published: 06/09/2023

Article Online First time: 15 days

Article editing time: 294 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology