Year 2020 / Volume 112 / Number 6
Original
Association of celiac disease in patients with multiple sclerosis in Tuscany

474-476

DOI: 10.17235/reed.2020.6123/2018

Barbara Piccini, Monica Ulivelli, Maria Pia Amato, Sabina Bartalini, Mario Falcini, Marta Giannini, Eliana Magnani, Luca Massacesi, Anna Maria Repice, Marina Vascotto, Salvatore Grosso,

Abstract
Background and study purpose: to describe the comorbidity of celiac disease among a large cohort of multiple sclerosis patients in Tuscany. Methods: the association of celiac disease among multiple sclerosis adult patients (n=2050) was retrospectively evaluated. Results: 13 patients were diagnosed with celiac disease, the female:male ratio was 3.3:1 and the median age at diagnosis was 34.2 years (SD 13). Seventy-seven per cent of subjects complained about gastrointestinal symptoms. IgA anti- transglutaminase was positive in 85 % of cases and there was 70 % of villous atrophy. Conclusions: the frequency of celiac disease among multiple sclerosis patients examined was lower than in the general population, 0.6 % vs 1 %)(p = 0.65).
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Piccini B, Ulivelli M, Amato M, Bartalini S, Falcini M, Giannini M, et all. Association of celiac disease in patients with multiple sclerosis in Tuscany. 6123/2018


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Publication history

Received: 14/12/2018

Accepted: 18/09/2019

Online First: 07/05/2020

Published: 08/06/2020

Article revision time: 266 days

Article Online First time: 510 days

Article editing time: 542 days


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