Year 2026 / Volume 118 / Number 3
Letter
Successful management of eosinophilic esophagitis with mometasone: an unusual therapeutic approach

189-190

DOI: 10.17235/reed.2025.11106/2025

Ana Lancho Muñoz, José María López Tobaruela, Paula Iglesias Conejero, Eduardo Redondo Cerezo,

Abstract
Eosinophilic esophagitis is a chronic, immune-mediated esophageal condition characterized by eosinophilic infiltration of the esophageal mucosa. This report discusses the case of a patient with EoE who showed significant clinical and histological improvement following treatment with mometasone, a corticosteroid rare used for this disease. Mometasone has shown promise due to its enhanced mucosal absorption and potent anti-inflammatory properties. In this case, the patient exhibited resolution of symptoms and marked reduction in endoscopic and histological involvement, suggesting that mometasone could serve as a viable alternative therapy in specific clinical scenarios.
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References
(1) Walgraeve S, Vanuytsel T. Novel corticosteroid formulations in the treatment of eosinophilic esophagitis: what is the evidence? AGEB 2023;86:437–48. https://doi.org/10.51821/86.3.11757.
(2) Syverson EP, Hait E, McDonald DR, Rubinstein E, Goldsmith JD, Ngo PD, et al. Oral viscous mometasone is an effective treatment for eosinophilic esophagitis. The Journal of Allergy and Clinical Immunology: In Practice 2020;8:1107–9. https://doi.org/10.1016/j.jaip.2019.08.042.
(3) Tytor J, Larsson H, Bove M, Johansson L, Bergquist H. Topically applied mometasone furoate improves dysphagia in adult eosinophilic esophagitis – results from a double-blind, randomized, placebo-controlled trial. Scandinavian Journal of Gastroenterology 2021;56:629–34. https://doi.org/10.1080/00365521.2021.1906314.
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Citation tools
Lancho Muñoz A, López Tobaruela J, Iglesias Conejero P, Redondo Cerezo E. Successful management of eosinophilic esophagitis with mometasone: an unusual therapeutic approach. 11106/2025


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Publication history

Received: 26/01/2025

Accepted: 03/02/2025

Online First: 11/02/2025

Published: 06/03/2026

Article Online First time: 16 days

Article editing time: 404 days


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