Year 2025 / Volume 117 / Number 7
Letter
Hepatopathy secondary to infiltration by malignant melanoma: diagnostic value of liver biopsy

407-409

DOI: 10.17235/reed.2024.10459/2024

Alejandro García Martínez, Álvaro Morales Prado, Jorge Martínez-Echevarría Gil-Delgado, Daniel Mateos Millán,

Abstract
We present the case of a 61-year-old male with no relevant history of interest who was admitted to hospital due to constitutional syndrome and discomfort in the right hypochondrium. On admission, abdominal ultrasound was performed with findings of chronic liver disease and innumerable well-defined hypoechogenic lesions of small size. Although the study was extended with other imaging tests, they did not provide more information than what was available at the time. Subsequently, an ultrasound-guided liver biopsy was performed with pathological anatomy compatible with infiltration by malignant melanoma. Subsequently, a search for the primary origin of the melanoma was performed and it was found in the right thigh. Hepatic involvement by melanoma is infrequent and both the symptoms and the findings in the complementary tests are non-specific, characteristics that make diagnosis difficult. Therefore, in these cases liver biopsy plays a fundamental role in the diagnosis.
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References
1. Tanaka K, Tomita H, Hisamatsu K, Hatano Y, Yoshida K and Hara A. Acute Liver Failure Associated with Diffuse Hepatic Infiltration of Malignant Melanoma of Unkown Primary Origin. Intern Med.2015.54:1361-1364.
2. Aierken Y, Zhu Y-F and Yang J-Y. Acute liver failure caused by metastatic malignant melanoma of liver. Med Case Rep Study Protoc.2021;2(3):1-3.
3. Lee Y, Lee J, Kim H, Park C, Jung J, Kim D, et al. Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma. Clin Endosc.2022;55:287-291.
4. Fusasaki T, Narita R, Hiura M, Abe S, Tabaru A, Hino R, et al. Acute hepatic failure secondary to extensive hepatic replacement by metastasic amelanotic melanoma: an autopsy case report. Clin J Gastroenterol.2010;3(6):327-31.
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García Martínez A, Morales Prado Á, Martínez-Echevarría Gil-Delgado J, Mateos Millán D. Hepatopathy secondary to infiltration by malignant melanoma: diagnostic value of liver biopsy. 10459/2024


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Publication history

Received: 05/04/2024

Accepted: 13/04/2024

Online First: 30/04/2024

Published: 08/07/2025

Article Online First time: 25 days

Article editing time: 459 days


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