Year 2026 / Volume 118 / Number 1
Letter
Validation of a rapid test for celiac disease detection in first-degree relatives — A prospective study

63-64

DOI: 10.17235/reed.2024.10791/2024

María Pascual Lorén, Ana Martín-Adrados, Rosa María González Cervera, Jorge Martínez Pérez, Ana Isabel Quintero García, Rosa Ana Muñoz Codoceo,

Abstract
Celiac disease (CD) is an autoimmune disorder triggered by gluten in genetically predisposed individuals, often diagnosed by detecting anti-tTG2 antibodies. First-degree relatives of CD patients are at high risk and require careful evaluation. We conducted a prospective study to validate CeliacDetect, a rapid immunochromatographic test that detects anti-tTG2 IgA antibodies in capillary blood within 10 minutes. Involving 95 first-degree relatives, the study showed that CeliacDetect had 100% sensitivity, specificity, positive predictive value, and negative predictive value. These results suggest CeliacDetect is a highly accurate, non-invasive screening tool for early CD detection.
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References
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Citation tools
Pascual Lorén M, Martín-Adrados A, González Cervera R, Martínez Pérez J, Quintero García A, Muñoz Codoceo R, et all. Validation of a rapid test for celiac disease detection in first-degree relatives — A prospective study. 10791/2024


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Publication history

Received: 12/09/2024

Accepted: 29/10/2024

Online First: 07/11/2024

Published: 14/01/2026

Article Online First time: 56 days

Article editing time: 489 days


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