Year 2021 / Volume 113 / Number 5
Original
Tailored Helicobacter pylori eradication therapy in obese patients undergoing bariatric surgery

345-347

DOI: 10.17235/reed.2020.7433/2020

Oscar Laudanno, Gabriel Ahumarán, Pablo Gollo, Marina Khoury, Marcelo Thomé, Patricia González,

Abstract
Objectives: to compare the efficacy and safety of a tailored quadruple concomitant therapy based on body weight, with the same scheme but with fixed doses in obese patients undergoing bariatric surgery. Methods: a prospective study was performed of 104 obese patients. Results: the weight-based therapy group achieved significantly higher eradication rates in the intention-to-treat analysis; 86.3 % (95 % CI: 74.3-93.2) vs 66.1 % (95 % CI: 52.6-77.3), p < 0.05. Relative risk: 1.31 (95 % CI: 1.05-1.63). Discontinuations and adverse events were similar in both groups. Conclusions: a tailored quadruple concomitant therapy based on body weight seems to be more effective than the standard quadruple concomitant therapy in obese patients.
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Laudanno O, Ahumarán G, Gollo P, Khoury M, Thomé M, González P, et all. Tailored Helicobacter pylori eradication therapy in obese patients undergoing bariatric surgery. 7433/2020


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Publication history

Received: 25/07/2020

Accepted: 07/08/2020

Online First: 27/11/2020

Published: 10/05/2021

Article revision time: 9 days

Article Online First time: 125 days

Article editing time: 289 days


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