Year 2020 / Volume 112 / Number 8
Letter
The development of type-1 autoimmune hepatitis after chronic hepatitis C (HCV) clearance by direct-acting antivirals (DAA)

664-665

DOI: 10.17235/reed.2020.6785/2019

Cristina Montón, M.ª Desamparados Escudero, Isabel Pascual,

Abstract
We present the case of a 72-year-old female in follow-up for chronic hepatitis due to hepatitis C virus (HCV) genotype 1b, with a liver stiffness measurement estimated by transient elastography in 2015 of 17 Kp and type 2 diabetes mellitus. She was treated daily with ledipasvir 90 mg and sofosbuvir 400 mg for 12 weeks. In March 2016, she achieved a sustained virological response (SVR) after 12 weeks and 24 weeks. She had a positive determination of antinuclear antibodies 7.9 in 2014.
Share Button
New comment
Comments
No comments for this article
References
1. Covini G, Bredi E, Badalamenti S, et al. Autoimmune Hepatitis During Ledipasvir/Sofosbuvir Treatment of Hepatitis C: A Case Report. Hepatol Commun. 2018 Sep 25;2(10):1179-1183. doi: 10.1002/hep4.1248. eCollection 2018 Oct.
2. Matsumoto K, Kikuchi K, Kajiyama Y, et al . Development of Autoimmune Hepatitis during Direct-acting Antiviral Therapy for Chronic Hepatitis C Virus Infection. Intern Med. 2018 Sep 15;57(18):2669-2673. doi:10.2169/internalmedicine.0613-17. Epub 2018 Apr 27.
3. Efe C, Heurgué-Berlot A, Ozaslan E et al. Late autoimmune hepatitis after hepatitis C therapy. Eur J gastroenterol Hepatol 2013 Nov;25(11):1308-11. doi: 10.1097/MEG.0b013e328361c704.
4. Terziroli Beretta-Piccoli B, Di Bartolomeo C, Deleonardi G, et al, Hepatitis C Cohort Study. Autoimmune liver serology before and after successful treatment of chronic hepatitis C by direct acting antiviral agents. J Autoimmun. 2019 Aug;102:89-95. doi: 10.1016/j.jaut.2019.04.019.
5. López Couceiro L, Gómez Domínguez E, Muñoz Gómez R et al. Healing of autoimmune hepatitis associated with hepatitis C virus infection treated with direct-acting antivirals. Rev Esp Enferm Dig. 2019 Feb;111(2):159-161. doi: 10.17235/reed.2018.5528/2018.
Citation tools
Montón C, Escudero M, Pascual I. The development of type-1 autoimmune hepatitis after chronic hepatitis C (HCV) clearance by direct-acting antivirals (DAA). 6785/2019


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1019 visits.
This article has been downloaded 130 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 02/12/2019

Accepted: 27/12/2019

Online First: 20/07/2020

Published: 30/07/2020

Article revision time: 21 days

Article Online First time: 231 days

Article editing time: 241 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology