Editorial
What may GLP1 receptor agonists contribute to the treatment of patients with non-alcoholic fatty liver disease?
587-589
Francisco Javier Escalada San Martín,
Non-alcoholic fatty liver disease (NAFLD) poses a challenge to health services both in developed and developing countries, with a significant increase in incidence and prevalence that is related to the...
Original
Usefulness of population pharmacokinetics to optimize the dosage regimen of infliximab in inflammatory bowel disease patients
590-597
Mayte Gil Candel, Juan José Gascón Cánovas, Rosa Gómez Espín, Isabel Nicolás de Prado, Lorena Rentero Redondo, Elena Urbieta Sanz, Carles Iniesta Navalón,
Introduction: infliximab is used in inflammatory bowel disease, which has a great inter-individual pharmacokinetic variability. Thus, it is necessary to individualize the therapy in many cases. The main...
Original
Impact of interval timing to surgery on tumor response after neoadjuvant treatment for gastric cancer
598-604
Juan Ocaña Jiménez, Pablo Priego, Marta Cuadrado, Luis Alberto Blázquez, Silvia Sánchez Picot, Paula Pastor Peinado, Federico Longo, Fernando López, María Alejandra Caminoa-Lizarralde, Julio Galindo,
Introduction: neoadjuvant chemotherapy (NACT) followed by radical surgery is the optimal approach for locally advanced gastric cancer (GC). Interval timing to surgery after NACT in GC is controversial....
Original
Endoscopic treatment of biliary complications after liver transplantation
605-608
María López Álvarez, Alejandra Otero, Maria Angeles Vázquez Millán, Francisco Suárez López, Pedro Alonso Aguirre,
Background: biliary complications are an important cause of morbidity and mortality after liver transplantation. Endoscopic retrograde cholangiopancreatography (ERCP) is a therapeutic option, which is...
Original
Prognostic significance of lymph node count in high-risk node-negative colon carcinoma
609-614
Patricia Martínez Ortega, Javier A. Cienfuegos, Jorge Baixauli, Carlos Sánchez Justicia, Marta Abengózar, Carlos Pastor Idoate, José Luis Hernández Lizoáin,
Background: the prognostic value of the number of lymph nodes isolated (< 12 versus ≥ 12) in the surgical specimen continues to be controversial. In this study, the impact of isolating fewer or more than...
Original
Differences between residual and primary choledocholithiasis in cholecystectomy patients
615-619
José Ruiz Pardo, Andrés García Marín, Francisco Javier Ruescas García, Miguel Jurado Román, Marcelo Scortechini, María Pilar Sagredo Rupérez, Juan Valiente Carrillo,
Introduction: choledocholithiasis can be primary from stones originally formed in the choledocho or secondary from stones that have migrated from the gallbladder to the choledocho. The objective of this...
Original
The association of dietary β-carotene and vitamin A intake on the risk of esophageal cancer: a meta-analysis
620-626
Kang Li, Bo Zhang,
Background and purpose: dietary β-carotene and vitamin A intake have shown some potential effect in the development of esophageal cancer. This meta-analysis was performed to investigate the association...
Original
The efficacy of glucagon-like peptide 1 receptor agonists in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials
627-635
Simin Fan, Xiaoyan Shi, Jia Yao, Min Zhong, Peimin Feng,
Background: non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of metabolic syndrome and is highly prevalent all over the world. New drugs are urgently needed for the...
Original
Predictive factors of clinical response to treatment with anti-TNF agents in ulcerative colitis: what have we learned from our patients?
636-641
Laura Ramos, Alejandro Hernández Camba, Raquel de la Barreda Heusser, Milagros Vela, Inmaculada Alonso-Abreu, Esther Rodríguez G., Marta Carrillo, Carlos Tardillo, Yolanda Rodríguez, Andrés Figueroa Marrero, Daniel Ceballos, Noelia Cruz, Lilian Kolle-Casso, Alejandro Jiménez Sosa,
Introduction: inhibitors of tumor necrosis factor alpha (anti-TNFs) are effective drugs for the treatment of moderate-to-severe ulcerative colitis (UC). However, many patients do not respond or lose therapeutic...
Review
New non-invasive biomarkers for colorectal cancer screening
642-648
Saray Duran-Sanchon, Cristina Herrera-Pariente, Leticia Moreira,
Colorectal cancer (CRC) is one of the most frequent neoplasia in developed countries and the second leading cause of cancer death in Spain. It develops through the accumulation of genetic and epigenetic...
Review
Comparison of the diagnostic efficacy of blue laser imaging with narrow band imaging for gastric cancer and precancerous lesions: a meta-analysis
649-658
Jingyuan Zhou, Huijie Wu, Chenglong Fan, Songda Chen, Aiqun Liu,
Background and aims: novel endoscopic techniques including narrowband imaging (NBI) and blue laser imaging (BLI) have led to the improved detection of early stage gastric cancer and precancerous lesions....
Digestive Diseases Image
Intrapancreatic accessory spleen versus a neuroendocrine pancreas tumor: a diagnostic challenge
659-660
Lucía Diego García, Alba Manuel Vazquez, Emilio Valbuena Durán, José Manuel Ramia Ángel,
The intrapancreatic accessory spleen is a congenital entity whose differential diagnosis is mainly raised with neuroendocrine tumors of the pancreas. Keeping in mind this unfrequent entity and careful...
Research letter
Extensive colonic pneumatosis. Conservative or Surgical approach?
661
Leticia Pérez Santiago, Ricardo Gadea Mateo, Raquel Alfonso Ballester,
Intestinal pneumatosis is a radiologic finding that consists of the presence of air in the intestinal wall. The etiology is extensive and can range from a benign entity to one that compromises the patients´...
Research letter
A huge rectal ulcer due to argon plasma coagulation in a patient with radiation proctitis
661-662
David Viso Vidal, Marcos Jiménez Palacios, Francisco Jorquera Plaza,
Radiation proctitis (RP) is a complication of radiotherapy in patients with pelvic cancer. A 64-year-old male underwent brachytherapy 2 years previously due to prostate cancer. Subsequently, he developed...
Research letter
The role of percutaneous endoscopic gastrostomy in the treatment of acute gastric volvulus
662-663
José Luis Romera Martínez, Adriana Ruano Campos, Andrés Sánchez Pernaute,
Gastric volvulus is an uncommon pathology that can occur acutely, in a chronic setting, or even as a casual finding. The primary kind occurs in 30% of patients. Secondary causes include hiatal hernia types...
Research letter
Dasatinib-induced colitis: discovering the side effects of immunotherapy
663-664
Víctor Jiménez Beltrán, Auxiliadora Bermúdez Alarcón, Olegario Castaño Fernández,
The effects of immunotherapy are numerous and are still being discovered. We present a case report of a patient who received dasatinib for chronic myeloid leukemia. A colonoscopy was performed due to a...
Research letter
The development of type-1 autoimmune hepatitis after chronic hepatitis C (HCV) clearance by direct-acting antivirals (DAA)
664-665
Cristina Montón, M.ª Desamparados Escudero, Isabel Pascual,
We present the case of a 72-year-old female in follow-up for chronic hepatitis due to hepatitis C virus (HCV) genotype 1b, with a liver stiffness measurement estimated by transient elastography in 2015...
Research letter
Prophylactic HIPEC with oxaliplatin might be of benefit in T4 and perforated colon cancer: another possible interpretation of the COLOPEC results
666
Juan José Segura-Sampedro, Rafael Morales-Soriano,
The COLOPEC trial failed to show evidence for improved relapse-free survival (RFS) between the two study groups: 80,9% (95% CI 73.3–88.5) in the experimental group and 76.2 % (68.0-84.4) in the control...
Research letter
Biopsy for hepatocellular carcinoma: only occasionally
666-667
Javier Crespo, Álvaro Díaz González,
We would like to highlight that the non-invasive criteria for HCC diagnosis, defined by the presence of hyperenhancement in the arterial phase (wash-in) followed by hypoenhancement (wash-out) in venous...
Research letter
Hepatocarcinoma diagnosis. Reflection is required
667-668
Andrea Illán Varela,
The editorial published in this same journal entitled "Sombras del tratamiento actual del hepatocarcinoma en España: una verdad incómoda" has awakened the need to review the available scientific literature...