Año 2023 / Volumen 115 / Número 12
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Plasma levels of intestinal fatty-acid binding protein (I-FABP), abdominal distension and hydrogen concentration after lactitol small intestinal bacterial overgrowth (SIBO) test

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DOI: 10.17235/reed.2023.9578/2023

Carlos Maroto, Aida Fiz-López, Raquel Pastor, David Bernardo, José Antonio Garrote, Eduardo Arranz, Luis Fernández Salazar,

Resumen
Breath tests with glucose, lactulose or lactitol are useful for diagnosis of small intestinal bacterial overgrowth (SIBO). Nevertheless, they have suboptimal sensitivity and specificity and, indeed, are positive in a considerable number of patients with irritable bowel syndrome (IBS). The complexity in the management of patients with functional intestinal disorders and the availability of these tests are leading to frequent diagnoses of SIBO. Intestinal Fatty-Acid Binding protein (I-FABP) is a protein present in the cytosol of intestinal epithelial cells. Its plasmatic levels have been related to different enteropathies and, therefore, could be a marker of early intestinal damage with unconfirmed clinical utility. Hence, we have studied the plasmatic I-FABP level of patients who are requested a lactitol test to confirm SIBO and related it to clinical and laboratory characteristics and SIBO test results.
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Bibliografía
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Instrucciones para citar
Maroto C, Fiz-López A, Pastor R, Bernardo D, Garrote J, Arranz E, et all. Plasma levels of intestinal fatty-acid binding protein (I-FABP), abdominal distension and hydrogen concentration after lactitol small intestinal bacterial overgrowth (SIBO) test. 9578/2023


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Ficha Técnica

Recibido: 06/03/2023

Aceptado: 11/03/2023

Prepublicado: 17/03/2023

Publicado: 12/12/2023

Tiempo de prepublicación: 11 días

Tiempo de edición del artículo: 281 días


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