Year 2018 / Volume 110 / Number 6
Case Report
Hepatitis E virus in neurological disorders: a case of Parsonage-Turner syndrome

402-403

DOI: 10.17235/reed.2018.5506/2018

María Sánchez Azofra, Miriam Romero Portales, Lucia Tortajada Laureiro, Javier García-Samaniego, Pedro Mora Sanz,

Abstract
Hepatitis E virus (HEV) infection is an emerging disease in developed countries with a broad clinical spectrum. In the absence of immunodeficiency or pregnancy, it is a mild and almost asymptomatic condition in most cases. However, extrahepatic manifestations, including neurological conditions, are common and may occasionally lead to permanent neurological sequelae. Herein, we report the case of an immunocompetent patient who was admitted to our hospital with paresthesia and weakness in both the upper extremities associated with anicteric-elevated transaminases. The diagnosis was Parsonage-Turner syndrome (neuralgic amyotrophy) secondary to HEV infection. The diagnosis was reached via electromyography and serology tests. Neuralgic amyotrophy (NA) is a demyelinating axonal disease that affects the brachial plexus and is associated with HEV infection in up to 10% of cases. We also emphasize the importance of requesting HEV serology in patients with neurological disease, especially with the involvement of the peripheral nervous system. Although the role of ribavirin remains to be fully determined, early diagnosis and treatment may result in an improved prognosis, thereby minimizing neurological sequelae.
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Sánchez Azofra M, Romero Portales M, Tortajada Laureiro L, García-Samaniego J, Mora Sanz P. Hepatitis E virus in neurological disorders: a case of Parsonage-Turner syndrome. 5506/2018


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Publication history

Received: 29/01/2018

Accepted: 22/02/2018

Online First: 12/04/2018

Published: 31/05/2018

Article revision time: 19 days

Article Online First time: 73 days

Article editing time: 122 days


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