Year 2026 / Volume 118 / Number 2
Letter
Hepatic myelopathy improved by embolization of spontaneous portosystemic shunt and partial splenic artery embolization ‒ Literature review

119-120

DOI: 10.17235/reed.2025.11451/2025

Fei Liu, Jiran Deng, Zhi Li, zhong Huang,

Abstract
Hepatic myelopathy (HM) is a serious and debilitating complication associated with chronic liver disease. Currently, there is no definitive treatment; however, it is widely accepted that early liver transplantation and stent-restricted surgery may alleviate HM to some extent. We report a case of an adult male with a history of hepatitis B cirrhosis who developed a complex spontaneous shunt following portal vein occlusion, which resulted in recurrent hepatic encephalopathy and was later complicated by HM. We successfully relieved HM in this patient through embolization of the inferior mesenteric venous shunt and a portion of the splenic artery. This approach may offer a feasible alternative in selected patients not eligible for liver transplantation.
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References
1. Bourgeois, S., Hepatic myelopathy. Neurology, 1993. 43(3 Pt 1): p. 629.
2. Weissenborn, K., et al., Liver transplantation improves hepatic myelopathy: evidence by three cases. Gastroenterology, 2003. 124(2): p. 346-51.
3. Nardone, R., et al., Corticospinal involvement in patients with a portosystemic shunt due to liver cirrhosis: a MEP study. J Neurol, 2006. 253(1): p. 81-5.
4. Philips, C.A., L. Kumar, and P. Augustine, Partial splenic artery embolization for severe hepatic myelopathy in cirrhosis. Hepatology, 2018. 67(3): p. 1169-1171.
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Liu F, Deng J, Li Z, Huang z. Hepatic myelopathy improved by embolization of spontaneous portosystemic shunt and partial splenic artery embolization ‒ Literature review . 11451/2025


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Publication history

Received: 01/07/2025

Accepted: 21/07/2025

Online First: 29/09/2025

Published: 09/02/2026

Article Online First time: 90 days

Article editing time: 223 days


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