Year 2022 / Volume 114 / Number 8
Letter
XI factor deficiency as cause of recurrent gastrointestinal bleeding

504-505

DOI: 10.17235/reed.2022.8669/2022

Laura Juan-Casamayor, Esteban Fuentes-Valenzuela, Carmen Alonso-Martín, Elena Fernández-Fontecha, Félix García-Pajares,

Abstract
We present the case of a 73-year-old woman with no relevant medical history. She was admitted for a 3-month intermittent melena. The physical exam was unremarkable. Blood tests revealed anemia (hemoglobin 7.4 g/dL), raised urea (69 mg/dL), normal platelets and coagulation. Gastroscopy was performed with active oozing bleeding in the fundus and gastric body. Endoscopic fulguration of the potential lesions with holmium laser was performed. She was discharged with resolution of the symptoms and analytical improvement. However, the patient required hospitalization two weeks later due to recurrence of melena and anemia.
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References
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2. Gomez K, Bolton-Maggs P. Factor XI deficiency. Haemophilia. 2008;14(6):1183–9.
3. Ling G, Kagdi H, Subel B, et al. Safety and efficacy of factor XI (FXI) concentrate use in patients with FXI deficiency: a single-centre experience of 19 years. Haemophilia. 2016 May;22(3):411–8
4. Peyvandi F, Palla R, Menegatti M, et al. Coagulation factor activity and clinical bleeding severity in rare bleeding disorders: Results from the European Network of Rare Bleeding Disorders. J Thromb Haemost. 2012;10(4):615–21.
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Citation tools
Juan-Casamayor L, Fuentes-Valenzuela E, Alonso-Martín C, Fernández-Fontecha E, García-Pajares F. XI factor deficiency as cause of recurrent gastrointestinal bleeding. 8669/2022


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Publication history

Received: 31/01/2022

Accepted: 08/03/2022

Online First: 17/03/2022

Published: 27/07/2022

Article Online First time: 45 days

Article editing time: 177 days


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