Year 2017 / Volume 109 / Number 2
Case Report
Mixed adenoneuroendocrine carcinoma (MANEC) of the gastroesophageal junction: a case report and review of the literature

160-162

DOI: 10.17235/reed.2016.4315/2016

José Francisco Juanmartiñena, Ignacio Fernández-Urién, Alicia Córdoba, Coro Miranda, Ana Borda,

Abstract
Esophageal cancer is the fourth most common neoplasm of the gastrointestinal tract. It is responsible for 1.7% of all deaths related with cancer. The two main types of esophageal cancer are squamous cell carcinoma and adenocarcinoma. Other types of esophageal cancer are uncommon. We present a 57-year-old man admitted to the hospital with nausea and vomiting due to a high-grade malignant mixed adenoneuroendocrine carcinoma of the gastroesophageal junction. The patient underwent Ivor-Lewis esophagectomy and adyuvant chemoradiotherapy. At 8-month follow-up he was alive without evidence of recurrence.
Share Button
New comment
Comments
No comments for this article
References
1. Rindi G, Arnold R, Bosman FT, et al. Nomenclature and classification of neuroendocrine neoplasms of the digestive system. In WHO Classification of Tumours of the Digestive System, 4th ed. Bosman TF, Carneiro F, Hruban R.H., Theise N.D (Eds); Internantional Agency for Research on cancer (IARC). Lyon, 2010. p.13.
2. Hasegawa S, Yoshikawa T. Adenocarcinoma of the esophagogastric junction:incidence, characteristics, and treatment strategies. Gastric Cancer 2010;13:63–73
3. Cordier R. Les cellules argentaffines dans les tumeurs intestinales. Arch. Int. Med. Exp 1924;1:9-74.
4. Solcia E, Kloppel G, Sobin LH. Histological typing of endocrine tumours. In: WHO International Histological Classification of Tumours, 2nd Springer: Berlin, Germany 2000.
5. La Rosa S, Marando A, Sessa F, et al. MANECs of the gastrointestinal tract: an update. Cancers 2012;4:11–30
6. Kitajima T, Kaida S, Lee S et al. Mixed adeno(neuro)endocrine carcinoma arising from the ectopic gastric mucosa of the upper thoracic esophagus.World J Surg Oncol 2013;11:218
7. Jain A, Singla S, Jagdeesh KS, et al. Mixed adenoneuroendocrine carcinoma of cecum: a rare entity. J Clin Imaging Sci 2013;3:10
8. Kim JJ, Kim JY, Hur H et al. Clinicopathologic significance of gastric adenocarcinoma with neuroendocrine features. J Gastric Cancer 2011;11:195–9.
9. Gurzu S, Kadar Z, Bara T,et al. Mixed adenoneuroendocrine carcinoma of gastrointestinal tract: report of two cases. World J Gastroenterol 2015;21:1329-33.
10. Veits L, Lang-Schwarz C, Volkholz H, et al. Mixed adenoneuroendocrine carcinoma (MANEC) of the esophagogastric junction predominantly consisting of poorly differentiated neuroendocrine carcinoma. Endoscopy 2013; 45(Supl. 2):16–7.
Citation tools
Juanmartiñena J, Fernández-Urién I, Córdoba A, Miranda C, Borda A. Mixed adenoneuroendocrine carcinoma (MANEC) of the gastroesophageal junction: a case report and review of the literature. 4315/2016


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 279 visits.
This article has been downloaded 107 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 09/03/2016

Accepted: 14/03/2016

Online First: 21/03/2016

Published: 31/01/2017

Article revision time: 2 days

Article Online First time: 12 days

Article editing time: 328 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology