Year 2023 / Volume 115 / Number 5
Letter
Varicella zoster virus encephalitis: a potentially serious complication during treatment with vedolizumab

271-272

DOI: 10.17235/reed.2022.9121/2022

Miriam Celada-Sendino, Lorena Carballo-Folgoso, Ruth de Francisco, Isabel Pérez-Martínez, Andrés Castaño-García, Sabino Riestra,

Abstract
Vedolizumab is a monoclonal antibody that has demonstrated efficacy and a good safety profile in patients with inflammatory bowel disease. Varicella zoster virus encephalitis is a potentially serious complication not previously described with its use, highlighting the importance of vaccination, as well as early diagnosis and treatment of infections in this type of patients.
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References
1. Colombel J-F, Sands BE, Rutgeerts P, et al. The safety of vedolizumab for ulcerative colitis and Crohn’s disease. Gut 2017;66:839–851.
2. Khan N, Patel D, Trivedi C, et al. Overall and Comparative Risk of Herpes Zoster With Pharmacotherapy for Inflammatory Bowel Diseases: A Nationwide Cohort Study. Clin Gastroenterol Hepatol. 2018;16:1919-1927.
3. Gupta G, Lautenbach E, Lewis JD. Incidence and risk factors for herpes zoster among patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2006;4:1483-90.
4. Hernández Martínez A, Navajas Hernández P, Martín Rodríguez MDM, et al. Efficacy and safety of tofacitinib in the treatment of ulcerative colitis: real-life experience in Andalusia. Rev Esp Enferm Dig. 2022.
5. Garbo GM, Macaluso FS, Renna S, et al. Herpes Zoster Eruption During Vedolizumab Therapy: A Simple Coincidence or More? Inflamm Bowel Dis. 2020;26:e51-e52.
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Citation tools
Celada-Sendino M, Carballo-Folgoso L, de Francisco R, Pérez-Martínez I, Castaño-García A, Riestra S, et all. Varicella zoster virus encephalitis: a potentially serious complication during treatment with vedolizumab. 9121/2022


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Publication history

Received: 04/08/2022

Accepted: 02/09/2022

Online First: 23/09/2022

Published: 05/05/2023

Article Online First time: 50 days

Article editing time: 274 days


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