Year 2020 / Volume 112 / Number 1
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Year 2020 / Volume 112 / Number 1

Original

Clinical validation of Endofaster® for a rapid diagnosis of Helicobacter pylori infection

23-26

Eugenia Sánchez Rodríguez, Rubén Sánchez Aldehuelo, Raquel Ríos León, Rosa María Martín Mateos, Ana García García de Paredes, Carlos Martín de Argila, Alejandra Caminoa, Agustín Albillos, Enrique Vázquez-Sequeiros,

Background: this study aimed to evaluate the diagnostic accuracy of the Endofaster® for the detection of Helicobacter pylori. Methods: during upper gastrointestinal endoscopy, gastric juice was aspirated to perform an analysis using the Endofaster®. This test was considered as positive when the ammonium concentration was > 67 ppm, negative when < 57 ppm and weakly positive between 57 and 67. Biopsy specimens were also taken as the gold standard. Results: among the 86 patients enrolled in the study, the Endofaster® result was positive in 23.7%, negative in 54.7% and weakly positive in 11.6%, whereas infection was detected via histology in 38.4% of patients. The accuracy was 81.4%, with a Kappa value of 0.57. Conclusions: the Endofaster® could be useful to perform a rapid diagnosis of Helicobacter pylori infection (area under the curve = 0.81).

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Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
© 2020 The Spanish Journal of Gastroenterology