Year 2025 / Volume 117 / Number 11
Letter
Lymphocytic esophagitis and ringed esophagus

701

DOI: 10.17235/reed.2025.11273/2025

Vitorino M. Santos, Kin Modesto Sugai,

Abstract
Lymphocytic esophagitis is an uncommon condition characterized by the presence of intraepithelial lymphocytosis and lack of eosinophils in the esophageal biopsy samples. The main clinical manifestations include dysphagia, heartburn, and vomiting; endoscopic changes are absent in up to 30% of cases, and may mimic the common gross aspects of an eosinophilic esophagitis as rings, longitudinal furrows, and stenosis. The authors emphasize the role of this diagnosis confirmation as early as possible, with prompt and adequate management aiming to avoid eventual unfavorable outcomes. The objective of this manuscript is to emphasize the case study of an infrequent entity.
New comment
Comments
No comments for this article
References
1. González Otero L, Seoane Blanco L, García Gómez A, Gómez Rivas M, Armesto Pérez A, López Rosés L. Lymphocytic esophagitis - a little-known cause of dysphagia. Rev Esp Enferm Dig. 2024. doi: 10.17235/reed.2024.10656/2024. Epub ahead of print.
2. Aboona MB, Kosako Yost K, Muńa Aguon P, Fung BM, Nanda R. Lymphocytic esophagitis presenting with food impaction. Cureus. 2023;15(8):e42873. doi: 10.7759/cureus.42873.
3. Jradi A, Khoury KM, Karam K, El Hajj DII, Fiani E. Lymphocytic esophagitis: navigating an uncharted territory. J Investig Med High Impact Case Rep. 2025;13:23247096251313734. doi: 10.1177/23247096251313734.
4. Koleva M, Raby M, Dikov D. Lymphocytic esophagitis associated with chronic severe psoriasis: a case report with special reference to programmed death-ligand 1 expression. Cureus. 2024;16(10):e70815. doi: 10.7759/cureus.70815.
5. Schoepfer A, Asikainen S, Biedermann L, Kreienbuehl A, Godat A, Dommann C, et al. Swallowed topical tacrolimus induces clinical and histological remission in a subset of patients with severe lymphocytic esophagitis. Inflamm Intest Dis. 2025;10(1):41-49. doi: 10.1159/000542812.
Related articles

Letter

Deceiving duodenal erosion: a fishbone lies beneath

DOI: 10.17235/reed.2024.10872/2024

Letter

A young male with primary hepatic epithelioid hemangioendothelioma

DOI: 10.17235/reed.2024.10733/2024

Letter

An unusual colon mass

DOI: 10.17235/reed.2024.10613/2024

Letter

Ovarian metastasis from pancreatic ductal carcinoma

DOI: 10.17235/reed.2024.10595/2024

Letter

Ogilvie, when medical and endoscopic treatment fail

DOI: 10.17235/reed.2024.10287/2024

Letter

Endoscopic treatment of Barrett´s esophagus

DOI: 10.17235/reed.2024.10201/2023

Letter

Calcifying fibrous tumor and pathological analysis

DOI: 10.17235/reed.2023.9739/2023

Letter

Endoscopic observation of a rare duodenal tumor

DOI: 10.17235/reed.2023.9679/2023

Editorial

Recent advances in the diagnosis and management of Wilson’s disease

DOI: 10.17235/reed.2023.9633/2023

Letter

Hepatosplenic T-cell lymphoma and inflammatory bowel disease

DOI: 10.17235/reed.2023.9472/2023

Letter

New technique for the endoscopic removal of long foreign bodies

DOI: 10.17235/reed.2023.9398/2022

Letter

Vaginal lesion as first manifestation of colorectal disease

DOI: 10.17235/reed.2022.9270/2022

Letter

An uncommon colonic polyp

DOI: 10.17235/reed.2022.9160/2022

Digestive Diseases Image

An unusual cause of a protuberant lesion of the gastric antrum

DOI: 10.17235/reed.2022.8771/2022

Letter

Sigmoid colon Schwannoma simulating colon cancer

DOI: 10.17235/reed.2022.8684/2022

Digestive Diseases Image

Abdominal cocoon sign: an unusual cause of intestinal obstruction

DOI: 10.17235/reed.2021.8057/2021

Letter

POEMS syndrome: an uncommon cause of peritoneal effusion

DOI: 10.17235/reed.2021.8027/2021

Digestive Diseases Image

Phlebosclerotic colitis: an unusual cause of abdominal pain and hematochezia

DOI: 10.17235/reed.2020.7358/2020

Review

New non-invasive biomarkers for colorectal cancer screening

DOI: 10.17235/reed.2020.7233/2020

Editorial

Reflex testing. A key tool for the elimination of hepatitis C

DOI: 10.17235/reed.2020.7201/2020

Letter

Chilaiditi’s and Ogilvie syndromes

DOI: 10.17235/reed.2020.7036/2020

Letter

Hepatocarcinoma diagnosis. Reflection is required

DOI: 10.17235/reed.2020.6845/2019

Letter to the Editor

Sternal cutaneous metastasis of hilar cholangiocarcinoma

DOI: 10.17235/reed.2017.4979/2017

Original

Neurogenic ppendicopathy. A report of 8 cases

DOI: 10.17235/reed.2017.4520/2016

Letter to the Editor

About human taeniasis and Taenia saginata diagnosis by endoscopy

DOI: 10.17235/reed.2016.4297/2016

Case Report

Primary esophageal melanoma: report of a case

DOI: 10.17235/reed.2016.3908/2015

Letter to the Editor

Unusual course of epiploic appendicitis

DOI: 10.17235/reed.2015.3796/2015

Citation tools
M. Santos V, Modesto Sugai K. Lymphocytic esophagitis and ringed esophagus . 11273/2025


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 13 visits.
This article has been downloaded 0 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 07/04/2025

Accepted: 11/04/2025

Online First: 12/05/2025

Published: 11/11/2025

Article Online First time: 35 days

Article editing time: 218 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2025 y Creative Commons. The Spanish Journal of Gastroenterology