Year 2025 / Volume 117 / Number 10
Letter
Cardiac surgery and acute hepatitis B - Use of the Seraph™ 100 hemofilter

594-595

DOI: 10.17235/reed.2024.10579/2024

Bárbara Segura-Méndez, Álvaro Fuentes-Martín, Yolanda Carrascal,

Abstract
We present a case of a 55-year-old male, presenting with angina symptoms with electrocardiographic changes and a panfocal systolic murmur radiating to the carotids. He had a primary HBV infection 8 months ago, without antiviral treatment. Echocardiography showed critical aortic valve stenosis (area: 0.53 cm2/m2). No coronary lesions were found on coronary angiography. Blood analysis revealed AST/GOT of 96 U/L and ALT/GPT 150 U/L. The serological profile revealed positive IgM anti-HBc, anti-HBc, anti-HBs and anti-HBe antibodies, with an increasing viral load (VL). The abdominal ultrasound identified mild hepatic fibrosis (F3) with minimal steatosis. Mechanical aortic prosthetic valve replacement was performed under CPB. The Seraph™ 100 filter was incorporated into the CPB circuit to reduce the risk of HBV contamination, infection and liver failure. The postoperative VL was monitored (Table 1). Liver function tests showed peak levels of bilirubin 0.66 mg/dL, AST/GOT 58 U/L, ALT/GPT 74 U/L at 6 hours post-surgery, with recovery of normal ranges at 48 hours post-surgery.
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Segura-Méndez B, Fuentes-Martín Á, Carrascal Y. Cardiac surgery and acute hepatitis B - Use of the Seraph™ 100 hemofilter. 10579/2024


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Publication history

Received: 04/06/2024

Accepted: 03/07/2024

Online First: 01/08/2024

Published: 10/10/2025

Article Online First time: 58 days

Article editing time: 493 days


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