Year 2018 / Volume 110 / Number 11
Case Report
Topical mesalazine as a cause of Stevens-Johnson syndrome

736-738

DOI: 10.17235/reed.2018.5429/2017

Andrea Núñez Ortiz, Claudio Trigo Salado, María Dolores de la Cruz Ramírez, José Manuel Herrera Justiniano, Eduardo Leo Carnerero,

Abstract
Mesalazine is a drug routinely used in ulcerative colitis and usually has few side effects. There have been reports of uncommon cases of severe mucocutaneous damage, such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), induced by salicylates. It is important to diagnose these promptly due to the high morbidity and mortality rates. We describe the case of a 46-year-old female with ulcerative proctitis, who developed SJS following topical mesalazine use. The lesions responded well to intravenous corticosteroids after discontinuation of the drug.
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References
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Núñez Ortiz A, Trigo Salado C, de la Cruz Ramírez M, Herrera Justiniano J, Leo Carnerero E. Topical mesalazine as a cause of Stevens-Johnson syndrome. 5429/2017


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Publication history

Received: 17/12/2017

Accepted: 29/04/2018

Online First: 22/06/2018

Published: 30/10/2018

Article revision time: 92 days

Article Online First time: 187 days

Article editing time: 317 days


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