Year 2025 / Volume 117 / Number 10
Letter
Clinical-pathological correlation of various symptoms in the diagnosis of pediatric eosinophilic esophagitis

615-616

DOI: 10.17235/reed.2024.10812/2024

Julio César Moreno-Alfonso, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,

Abstract
Eosinophilic esophagitis (EoE) is an immune-mediated disorder of the esophagus with a broad spectrum of clinical presentations. Dysphagia and food impaction are the cardinal symptoms; however, their diagnostic utility remains controversial in pediatric populations. This study evaluates the clinical-pathological association of different symptoms with EoE. We conducted an analytical study of patients under 15 years of age who underwent esophagoscopy at a pediatric hospital between 2015 and 2022 due to suspected EoE (Reg. 341E/2023). The prevalence of various symptoms and medical histories was compared, along with their association with histopathological abnormalities, between patients with EoE and those without the disease (NEoE). A total of 24 EoE patients and 17 NEoE children were included.
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References
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2. Lingblom C, Käppi T, Bergquist H, et al. Differences in eosinophil molecular profiles between children and adults with eosinophilic esophagitis. Allergy. 2017;72(9):1406-1414. DOI: 10.1111/all.13140
3. Gutiérrez Junquera C, Fernández Fernández S, Domínguez-Ortega G, et al. Recommendations for the diagnosis and practical management of paediatric eosinophilic oesophagitis. An Pediatr (Engl Ed). 2020;92(6):376.e1-376.e10. DOI: 10.1016/j.anpedi.2020.04.007
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Moreno-Alfonso J, Barbosa-Velásquez S, Molina Caballero A, Pérez Martínez A, Yárnoz Irazábal M. Clinical-pathological correlation of various symptoms in the diagnosis of pediatric eosinophilic esophagitis. 10812/2024


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Publication history

Received: 21/09/2024

Accepted: 27/09/2024

Online First: 18/10/2024

Published: 10/10/2025

Article Online First time: 27 days

Article editing time: 384 days


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