Year 2026 / Volume 118 / Number 2
Letter
Interstitial pneumonitis due to everolimus in a liver transplant recipient

123

DOI: 10.17235/reed.2024.10887/2024

Pere Vaquer-Grimalt, Natalia Chausse, Maria Dolors Ramis Estelrich, María Belén Núñez, Aina Escarda, Llucia Bonet, Lydia Sastre Oliver, Margalida Vanrell,

Abstract
This is a case report of a patient with a history of liver transplant who developed interstitial pneumonitis due to immunosuppressive treatment. Everolimus-induced pneumonitis in liver transplant recipients is a rare condition. This observation aims to highlight the significance of being aware of this condition, being suspicious of it, and getting a proper diagnosis and treatment.
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References
1. Siddiqui AS, Zimmerman JL. Everolimus associated interstitial pneumonitis in a liver transplant patient. Respir Med Case Rep. 2016;19:15-17. Published 2016 Jun 14. doi:10.1016/j.rmcr.2016.06.004
2. Molas-Ferrer G, Soy-Muner D, Anglada-Martínez H, et al. Interstitial pneumonitis as an adverse reaction to mTOR inhibitors. Nefrologia. 2013;33(3):297-300. doi:10.3265/Nefrologia.pre2013.Jan.11439
3. Velioglu A, Eryuksel E, Cimsit C, et al. Late Pulmonary Toxicity Associated With Everolimus in a Renal Transplant Patient and Review of the Literature. Exp Clin Transplant. 2018;16(4):491-494. doi:10.6002/ect.2015.0257
4. Klair J, Soota K, Voigt M. Everolimus-Induced Pneumonitis in a Liver Transplant Patient: An Emphasis on Management: 2285. American Journal of Gastroenterology 112:p S1252-S1253, October 2017.
5. Obri MS, Fahoury AM, Alhaj Ali S, et al. Pulmonary Complications of Everolimus in Liver Transplant Patients: A 10-Year Experience. Cureus. 2024 Jan 31;16(1):e53334. doi: 10.7759/cureus.53334. PMID: 38435956; PMCID: PMC10907112.
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Citation tools
Vaquer-Grimalt P, Chausse N, Ramis Estelrich M, Núñez M, Escarda A, Bonet L, et all. Interstitial pneumonitis due to everolimus in a liver transplant recipient. 10887/2024


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Publication history

Received: 24/10/2024

Accepted: 25/11/2024

Online First: 04/12/2024

Published: 09/02/2026

Article Online First time: 41 days

Article editing time: 473 days


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