Year 2025 / Volume 117 / Number 9
Letter
Cap polyposis refractory to drug treatment, including infliximab

529-530

DOI: 10.17235/reed.2024.10297/2024

Claudia Moreno Pimentel, Cristina Galindo García, Macarena Ariza Estepa, María Eloísa Naranjo Llamas, Claudia Palomar Ávila, Manuel Castro Fernández, María José Fobelo Lozano,

Abstract
Cap polyposis is a rare disease characterized by the presence of inflammatory polyps with an adherent fibrin sheath (“cap”), in variable number and size, in the rectum and sigmoid. It presents with tenesmus, mucous stools and rectorrhagia. There is currently no standardized treatment, having been treated empirically with aminosalicylates, oral or rectal steroids, metronidazole, H. pylori eradication therapy and infliximab with variable results. In refractory cases, endoscopic resection of polyps may be used and surgery may even be necessary. We present the case of a 36-year-old patient diagnosed in our center with cap polyposis, refractory to both pharmacological and endoscopic treatment, and therefore treatment with infliximab was decided out of indication. The case we present is the fourth case of cap polyposis treated with infliximab available in the current literature and highlights the difficulty of achieving a clinical response with pharmacological treatment, including biologic drugs such as infliximab.
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Citation tools
Moreno Pimentel C, Galindo García C, Ariza Estepa M, Naranjo Llamas M, Palomar Ávila C, Castro Fernández M, et all. Cap polyposis refractory to drug treatment, including infliximab. 10297/2024


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Publication history

Received: 23/01/2024

Accepted: 23/05/2024

Online First: 14/06/2024

Published: 15/09/2025

Article Online First time: 143 days

Article editing time: 601 days


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