Year 2019 / Volume 111 / Number 12
Letter
Umbilical metastasis of a pancreatic origin: Sister Mary Joseph’s nodule

977-978

DOI: 10.17235/reed.2019.6465/2019

Alberto Alejandro Marcacuzco Quinto, Oana Anisa Nutu, Iago Justo Alonso,

Abstract
An 84-year-old male patient presented with an umbilical mass. Upon examination, he had an umbilical lesion of approx. 2 cm that was nodular and painful on palpation. The abdominal CT showed a soft tissue mass of 20 x 22 mm in the umbilical subcutaneous tissue, associated with inflammatory changes. In addition, a hypodense tumor of 3.6 x 3.6 x 3.8 cm was seen located in the pancreatic tail, infiltrating the splenic hylum. Bloodwork revealed the following: haemoglobin 7.9 mg/dl, platelets: 175 x 100 /µl, prothrombin activity: 81%, INR: 1.13, Ca 19.9: 4289 U / ml, CEA: 4.38 ng / ml. The histopathological study of the umbilical lesion showed an adenocarcinoma with a moderately differentiated primary pancreatic origin, compatible with an umbilical metastasis of pancreatic cancer.
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References
1. Jia-Wei L, Dong-Lai M. An ominous sign from sister Mary Joseph. Lancet 2018;392:776.
2. Petch S, Sobota A, Saadeh F. Sister Mary Joseph nodule: an unusual site for endometrioid cancer metastasis. BMJ Case Rep 2019; 12: e229187
3. Omura T, Tamara Y, Koder R, et al. Pancreatic cancer manifesting as Sister Mary Joseph nodule during follow up of a patient with type 2 diabetes mellitus: A case report. Geriatr Gerontol Int. 2019; 19:363-363.
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Marcacuzco Quinto A, Nutu O, Justo Alonso I. Umbilical metastasis of a pancreatic origin: Sister Mary Joseph’s nodule. 6465/2019


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Publication history

Received: 26/06/2019

Accepted: 20/07/2019

Online First: 29/11/2019

Published: 05/12/2019

Article Online First time: 156 days

Article editing time: 162 days


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