Year 2022 / Volume 114 / Number 6
Letter
Ustekinumab for corticodependent immune-mediated colitis by pembrolizumab, an alternative for patients with concomitant liver injury

356-357

DOI: 10.17235/reed.2022.8618/2022

Flor M. Fernández-Gordón Sánchez, Elena Gómez-Domínguez, Diana Paredes Ruiz, Yolanda Rodríguez Gil, Ana Martín Algíbez, Inmaculada Fernández Vázquez, Pilar Martínez Montiel,

Abstract
Pembrolizumab, a programmed cell death receptor (PD-1) inhibitor, have improved the prognosis in several types of cancer. Despite the important clinical benefits, checkpoint inhibition have been associated with inflammatory and immune-related side effects (irAE).
Share Button
New comment
Comments
No comments for this article
References
1. Luque AM, Ontanilla-Clavijo G, Leo Carnerero E. Rev Esp Enferm Dig. 2020:112(11):889-890 DOI: 10.17235/reed.2020.6886/2020
2. Kurokawa K, Hara M, Iwakami SI, et al. Cholestatic Liver Injury Induced by Pembrolizumab in a Patient with Lung Adenocarcinoma. Intern Med. 2019;58(22):3283-3287. doi:10.2169/internalmedicine.2591-18
3. Queiroz NSF, Regueiro M. Safety considerations with biologics and new inflammatory bowel disease therapies. Curr Opin Gastroenterol. 2020 Jul;36(4):257-264. doi: 10.1097/MOG.0000000000000607. PMID: 31895234
4. Weijie Ma, Anusha Thomas, Yinghong Wang. Is chronic refractory colitis from immune checkpoint inhibitor associated with good cancer outcome? Journal of Clinical Oncology 2020 38:15_suppl, e15102-e15102
5. Thomas AS, Ma W, Wang Y. Ustekinumab for Refractory Colitis Associated with Immune Checkpoint Inhibitors. N Engl J Med. 2021 Feb 11;384(6):581-583. doi: 10.1056/NEJMc2031717. PMID: 33567198
Citation tools
Fernández-Gordón Sánchez F, Gómez-Domínguez E, Paredes Ruiz D, Rodríguez Gil Y, Martín Algíbez A, Fernández Vázquez I, et all. Ustekinumab for corticodependent immune-mediated colitis by pembrolizumab, an alternative for patients with concomitant liver injury. 8618/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1511 visits.
This article has been downloaded 187 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 19/01/2022

Accepted: 21/01/2022

Online First: 25/01/2022

Published: 07/06/2022

Article Online First time: 6 days

Article editing time: 139 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology