Year 2025 / Volume 117 / Number 10
Letter
Association of various symptoms and histological alterations in the diagnosis of pediatric ulcerative colitis

617-618

DOI: 10.17235/reed.2024.10834/2024

Julio César Moreno-Alfonso, Miguel Ángel Sánchez Durán, Sharom Barbosa-Velásquez, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,

Abstract
Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease (IBD) of the colon. Its presentation is varied, with the main symptoms being mucosanguineous diarrhea, abdominal pain, and weight loss. However, the diagnostic utility of these symptoms in pediatric populations is controversial. This study evaluates the clinicopathological association of different symptoms in UC through an analytical study of patients under 15 years of age who underwent upper and lower gastrointestinal endoscopy at a pediatric hospital between 2015 and 2022 for suspected IBD.
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References
1. Moreno-Alfonso JC, Delgado-Miguel C, Molina Caballero A, Pérez Martínez A, Yárnoz Irazábal MC. Correlation of endoscopic findings with histological alterations in pediatric ulcerative colitis. Rev Esp Enferm Dig. 2024. In Press. DOI: 10.17235/reed.2024.10755/2024
2. Flood E, Silberg DG, Romero B, Beusterien K, Erder MH, Cuffari C. Development of the pediatric daily ulcerative colitis signs and symptoms scale (DUCS): qualitative research findings. BMC Res Notes. 2017;10(1):491. DOI: 10.1186/s13104-017-2814-3
3. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition; Colitis Foundation of America; Bousvaros A, et al. Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America. J Pediatr Gastroenterol Nutr. 2007;44(5):653-74. DOI: 10.1097/MPG.0b013e31805563f3
4. Kugathasan S, Judd RH, Hoffmann RG, et al. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. J Pediatr. 2003;143(4):525-31. DOI: 10.1067/s0022-3476(03)00444-x
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Moreno-Alfonso J, Sánchez Durán M, Barbosa-Velásquez S, Molina Caballero A, Pérez Martínez A, Yárnoz Irazábal M, et all. Association of various symptoms and histological alterations in the diagnosis of pediatric ulcerative colitis. 10834/2024


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Publication history

Received: 02/10/2024

Accepted: 11/10/2024

Online First: 24/10/2024

Published: 10/10/2025

Article Online First time: 22 days

Article editing time: 373 days


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