Year 2023 / Volume 115 / Number 12
Letter
Intestinal tuberculosis presented as spindle cell pseudotumor in a HIV-positive case

723-724

DOI: 10.17235/reed.2023.9533/2023

Chengbo Li, Qingfu Zhang, Ying Wen,

Abstract
MSP is a rare and atypical form of benign granulomatous inflammation characterised by tumour-like local proliferation of spindle-shaped histiocytes containing acid-fast positive mycobacteria, which should be differentiated from neoplastic lesions. A 26-year-old Chinese man complained an intermittent and mild right lower abdominal pain for 5 months in May 2022.Histopathology of biopsy samples showed Mycobacterial spindle cell pseudotumor (MSP). The test of Mycobacterium tuberculosis detected by polymerase chain reaction using intestinal tissue slice was negative. The metagenomic next-generation sequencing (BGI-Shenzhen) using formalin-fixation and paraffin-embedded intestine samples confirmed Mycobacterium tuberculosis complex (MTBC).
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References
1.Sfeir MM, Schuetz A, Van Besien K,et al. Mycobacterial spindle cell pseudotumour: epidemiology and clinical outcomes. Journal of clinical pathology. 2018;71(7):626-30.DOI: 10.1136/jclinpath-2017-204777.
2.Basilio-de-Oliveira C, Eyer-Silva WA, Valle HA,et al. Mycobacterial spindle cell pseudotumor of the appendix vermiformis in a patient with aids. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. 2001;5(2):98-100.DOI: 10.1590/s1413-86702001000200008.
3.Krause JR, Findeis SK. Mycobacterial spindle cell pseudotumor in a woman with HIV. Proceedings (Baylor University Medical Center). 2020;33(3):438-9.DOI: 10.1080/08998280.2020.1753454.
4.Lim DD, Bushra A, Zhang H. Abdominal wall mycobacterial spindle cell pseudotumor lesion. Proceedings (Baylor University Medical Center). 2021;34(4):505-6.DOI: 10.1080/08998280.2021.1897340.
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Li C, Zhang Q, Wen Y. Intestinal tuberculosis presented as spindle cell pseudotumor in a HIV-positive case . 9533/2023


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Publication history

Received: 16/02/2023

Accepted: 21/02/2023

Online First: 03/03/2023

Published: 12/12/2023

Article Online First time: 15 days

Article editing time: 299 days


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