Year 2018 / Volume 110 / Number 8
Letter
A pneumoperitoneum due to intestinal cystic pneumatosis associated with a tyrosine kinase inhibitor

531-532

DOI: 10.17235/reed.2018.5588/2018

Alicia Martín-Lagos Maldonado, Cristina Lozano Cejudo, Antonio Sáenz Lozano,

Abstract
Pneumatosis cystoides intestinalis is characterized by multiple air-filled cysts in the intestine wall. A perforation causes pneumoperitoneum, frequently with minimal clinical affectation and do not require surgery at first in most cases. Recently, some cancer treatments, mainly molecular targeted therapy, have been associated with this complication. For this reason, radiologic findings of intestinal pneumatosis and/or secondary perforation during patient follow-up should be carefully interpreted. The clinical-analytical findings should always be considered. We report a case associated with the use of tyrosine kinase inhibitors in order to illustrate this point.
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References
1. De la Serna S, Luna A, De la Rosa H. Neumatosis intestinal y neumoperitoneo en contexto de tratamiento oncológico: un cambio de actitud. Rev Esp Enferm Dig 2018:110(1):68-69
2. Shinagare A, Howard S, Krajewski K, Zukotynski K, Jagannathan J et Ramaiya N. Pnumatosis intestinalis and bowel perforation associated with molecular targeted theray: an emerging problem and the role of radiologists in its management. AJR Am J Roentgenol. 2012 Dec;199(6):1259-65
3. Flaig TW, Kim FJ, La Rosa FG, Breaker K, Schoen J, Russ PD.Colonic pneumatosis and intestinal perforations with sunitinib treatment for renal cell carcinoma. Invest New Drugs. 2009 Feb;27(1):83-7.
4. Choi YA, Sim EH, Lee KE, Ko SY, Seo MJ, Yang YJ, et al. A case of pneumatosis intestinalis associated with sunitinib treatment for renal cell carcinoma. Korean J Gastroenterol. 2013 Jun;61(6):347-50.
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Martín-Lagos Maldonado A, Lozano Cejudo C, Sáenz Lozano A. A pneumoperitoneum due to intestinal cystic pneumatosis associated with a tyrosine kinase inhibitor . 5588/2018


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Publication history

Received: 10/03/2018

Accepted: 12/03/2018

Online First: 14/06/2018

Published: 30/07/2018

Article Online First time: 96 days

Article editing time: 142 days


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