Year 2025 / Volume 117 / Number 11

Editorial
627-629
DOI: 10.17235/reed.2025.11227/2025
Julio Pérez de la Serna y Bueno, Antonio Ruiz de León San Juan,
Chest pain is a common symptom in achalasia, particularly in younger patients, those with a shorter disease duration, and type III achalasia. Its frequency and intensity vary, sometimes resembling angina....
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Original
630-635
DOI: 10.17235/reed.2025.10646/2024
María Martínez Burgos, Javier Villena-Salinas, Senador Morán Sánchez, José Antonio Martínez Otón,
Introduction: colorectal cancer (CRC) screening is a strategy aimed at the early detection and treatment of this condition. Inviting asymptomatic individuals to participate in the program offers potential...
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Original
636-644
DOI: 10.17235/reed.2025.11190/2025
José María Huguet, Elena Gómez Delgado, Saioa Rubio, Patricia Suárez Álvarez, Isabel Vera Mendoza, José María Paredes, Alejandro Hernández Camba, Rocío Plaza Santos, Míriam Mañosa, Ramón Pajares Villarroya, Lucía Madero Velázquez, Pablo Vega, Regina Santos de Lamadrid, Naiara Michelena, Miriam García, Fernando Gomollón,
Introduction: Crohn’s disease (CD) and ulcerative colitis (UC) are characterized by persistent gastrointestinal inflammation. Timely, effective management is crucial to improve long-term patient outcomes....
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Original
645-653
DOI: 10.17235/reed.2025.11226/2025
Shu Wu, Huiling Kang, Er Huang, Wennan Wu, Lijuan Liu, Ronghua Chen,
Background and aim: chronic hepatitis B (CHB) affects millions globally and is a leading cause of liver cirrhosis and hepatocellular carcinoma. Nucleos(t)ide analogues (NAs) such as entecavir (ETV) and...
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Review
654-661
DOI: 10.17235/reed.2025.10555/2024
José Ruiz Pardo, Clara Eugenia Cobo Cervantes, Pedro Antonio Sánchez Fuentes,
Introduction: hip arthroplasty (HA) or knee arthroplasty (KA) may account for 24 % of the etiology of Ogilvie syndrome (OS), and OS is a rare complication of HA or KA. The objective of the study was to...
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Digestive Diseases Image
662-664
DOI: 10.17235/reed.2024.10151/2023
Daniel Conceição, Carolina Simões, Fátima Francisco, Isabel Claro,
Partially covered self-expanding metallic stents (SEMS) are the main recommendation for palliative treatment of malignant dysphagia. Delivering self-expanding metallic stents in stenosing oesophagus neoplasia’s...
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Digestive Diseases Image
665-666
DOI: 10.17235/reed.2024.10202/2023
Luís Correia Gomes, Margarida Rajão Saraiva, António Figueiredo, Sandra Faias,
Case 1: A 69-year-old male underwent magnetic resonance imaging (MRI) to evaluate hepatic hemangiomas that incidentally revealed a homogeneous hypervascular solid nodule (19 mm) in pancreatic tail. Differential...
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Digestive Diseases Image
667-668
DOI: 10.17235/reed.2024.10261/2024
Shin Kato, Mariko Tsukamoto, Taichi Murai, Yuta Koike,
Tract dilation is an essential step in completing endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS). EUS-HGS using a 22-gauge needle is currently attracting attention; however, the complexity...
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Letter
669-670
DOI: 10.17235/reed.2024.10664/2024
Sónia Barros, Luís Miguel Relvas, Isabel Malta Carvalho, Ana Rita Ventosa, Ana Margarida Vaz,
Renal cell carcinoma represents about 90% of all primary renal neoplasms. Clear cell renal cell carcinoma is the most common histological type, characterized by an aggressive clinical course due to its...
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Letter
670-671
DOI: 10.17235/reed.2024.10666/2024
Sónia Barros, Luís Miguel Relvas, Isabel Malta Carvalho, Catarina Cunha, Ana Margarida Vaz, Bruno Peixe,
We present a case of gastro-jejunal anastomotic stenosis due to the progression of malignant disease, successfully treated endoscopically by placing a lumen-apposing metal stent. This case illustrating...
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Letter
671-672
DOI: 10.17235/reed.2024.10595/2024
José Eloy Cobarro, José Manuel Ramia Ángel, Silvia Carbonell Morote, Josefa Marcos Sanmartín, Cándido Fernando Alcázar-López, Celia Villodre Tudela, Paola Melgar Requena, Celia García Vega,
A clinical case is presented about a rare presentation of pancreatic cancer. Firstly, pancreatic cancer rarely metastasizes to the ovary, and when it does, it usually presents in the form of peritoneal...
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Letter
672-673
DOI: 10.17235/reed.2024.10628/2024
Ana Plaza Fernández, Marta Fernández Carrasco, Olga Sánchez García,
Progressive familial intrahepatic cholestasis (PFIC) is a heterogeneous group of autosomal recessive disorders resulting from mutations in genes involved in bile secretion, characterized by chronic cholestasis....
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Letter
673-674
DOI: 10.17235/reed.2024.10661/2024
Flor M. Fernández-Gordón Sánchez, Celia Gómez Labrador, Carolina Georgiana Suárez Cabredo, Sandra Agudo Fernández, Daniel Riado Mínguez, Cristina Cuadrado Tiemblo, Antonio Hermosín Peña, Carlos Castaño Milla,
Bacterial peritonitis with loculated ascites in patients with liver cirrhosis can be a therapeutic challenge. We present the case of a patient with liver cirrhosis undergoing pre-transplant evaluation,...
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Letter
674-675
DOI: 10.17235/reed.2024.10665/2024
Diary Fall, Ana Gordo Ortega, Eric Allemant Castañeda, Edurne Amorena Muro, Saioa Rubio Iturria,
Primary eosinophilic gastrointestinal disorders are rare, characterized by eosinophilic infiltration without a secondary cause. Although esophageal involvement is most common, any part of the gastrointestinal...
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Letter
675-676
DOI: 10.17235/reed.2024.10668/2024
Pablo Salmón Olavarría, Martín Irabien Ortiz, Icíar de la Fuente Molinero, Ane Ugarte Bilbao, Sonia Cubillas Urkiola, José Gabriel Erdozain Castiella,
We present the case of a 71-year-old male with difficult to manage severe chronic diarrhea, who after multiple tests was finally diagnosed with Ménétrier's disease and had clinical improvement with treatment...
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Letter
676-677
DOI: 10.17235/reed.2024.10653/2024
De-Feng Li, Li-Yang Wang, Yan-Hui Tian, Rui-Yue Shi,
A-35-year-old woman presented our hospital with half a year's history of solid food dysphagia. An upper gastrointestinal endoscopy revealed a large submucosal mass in an esophageal diverticulum near the...
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Letter
677-678
DOI: 10.17235/reed.2023.10032/2023
Rodrigo Quera, Paulina Núñez Figueroa, Pía Zañartu, Luis Contreras,
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency in adults, with non-infectious gastrointestinal involvement present in up to 50 % of patients, with the small...
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Letter
678-679
DOI: 10.17235/reed.2024.10682/2024
Xiaorong Chen, Wenyuan Xie, Xiang Zhang, Jie Zhang, Yujun Zhu,
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune neuromuscular disease mediated by antibodies to voltage-gated calcium channels (VGCCs) at the neuromuscular junction. LEMS often presents as...
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Letter
679-680
DOI: 10.17235/reed.2024.10695/2024
Andrea Silva, Maria José Temido, Joana Madeira, Mariana Sant’Anna, Sandra Lopes, Mário Rui Silva, Pedro Figueiredo, Francisco Portela,
Introduction: Understand the cause of gastrointestinal symptoms compatible with irritable bowel syndrome (IBS) in patients with inflammatory bowel disease (IBD) in remission is challenging. Those patients...
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Letter
680-681
DOI: 10.17235/reed.2024.10699/2024
Yemin Liu, Fang Liu,
Splenic ectopic pregnancy refers to the implantation of fertilized ovum in the spleen, which occurs extremely rare. Due to the abundance of splenic blood and its fragile texture, the lethality of ruptured...
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Letter
681-682
DOI: 10.17235/reed.2024.10697/2024
Gema Marset, Samuel Fornos, Etna Masip, María Ángeles Calzado, Begoña Polo, María Roca, Carmen Ribes, Ester Donat,
In response to the article presented by Laura Rodríguez-Martínez et al., which discusses mucosal healing rates in celiac disease and the risk factors for persistent damage despite a gluten-free diet in...
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Letter
682-683
DOI: 10.17235/reed.2024.10660/2024
Cristina Galindo García, Claudia Moreno Pimentel, Reyes Serrano Giménez, Claudia Palomar Ávila, Manuel Castro Fernández, María José Fobelo Lozano,
Eosinophilic gastroenteritis is a rare, chronic inflammatory disease with eosinophil infiltration in the digestive tract. Treatment typically involves corticosteroids, but new therapies, including vedolizumab,...
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Letter
683-684
DOI: 10.17235/reed.2024.10681/2024
Joel Omar Jáquez-Quintana, César Ramos-Matamoros, Carlos Eugenio Gonzalez-Martinez, José Luis Herrera Elizondo,
The drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is an idiosyncratic drug-induced reaction that primarily affects the liver, lungs, and kidneys. While several organs are commonly...
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Letter
684-685
DOI: 10.17235/reed.2024.10840/2024
Álvaro Yagüe Parada, Rocío Calvo Hernández, Sergio Farrais Villalba,
Amoebiasis is an infection caused by the intestinal protozoan Entamoeba histolytica. It is transmitted via the faecal-oral route and primarily affects the intestinal tract and the liver. It is prevalent...
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Letter
685-686
DOI: 10.17235/reed.2024.10850/2024
Helena González Sánchez, Cristina Fuente Díaz, Marta García Calonge, Daniel Muíño Domínguez, Enrique Barbeito Castro,
Eosinophilic gastroenteritis (EG) is a rare disorder characterised by eosinophilic infiltration in the gastrointestinal tract. The disease most commonly occurs in the stomach, but can affect all sections...
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Letter
686-688
DOI: 10.17235/reed.2024.10963/2024
Julio César Moreno-Alfonso, Ada Molina Caballero, Sara Hernández Martín, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Abdominal pain is one of the leading causes of consultation in pediatrics, accounting for up to 10% of emergency department visits. The patient’s age, medical history, and physical examination are critical...
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Letter
688-689
DOI: 10.17235/reed.2024.10927/2024
Patricia Aranzábal Aguilar, Ainara Iriarte Rodríguez, Nerea Hervás Palacios, Julio Alfredo Bernuy Guevara, Íñigo Uribeetxebarria Agirre, Paul Gisasola, Leire Zubiaurre Lizarralde, Inés Gil Lasa,
The pancreatitis, panniculitis, polyarthritis (PPP) syndrome involves the association of pancreatic pathology, panniculitis of pancreatic origin, and polyarthritis secondary to intra-articular fat necrosis....
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Letter
689-690
DOI: 10.17235/reed.2024.10995/2024
María Gómez Otero, Andrea Guerro Moya, Eduardo Valdivieso Cortázar, Ángela Suárez Noya, José Souto Ruzo, Laura Pardeiro Mariño, Eladio Busto Lodeiro, Pedro Alonso Aguirre,
Eosinophilic gastroenteritis is an uncommon, chronic, immune-mediated condition characterized by eosinophilic infiltration that can affect any segment of the gastrointestinal tract. Clinical manifestations...
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Letter
691-692
DOI: 10.17235/reed.2025.11022/2024
Sónia Barros, Luís Relvas, Isabel Carvalho, Margarida Portugal, Catarina Cunha, Ana Margarida Vaz, Bruno Peixe,
Pancreatic panniculitis is a rare dermatological manifestation of pancreatic disorders, characterized by painful, erythematous nodules. We present the case of an 84-year-old woman with acute pancreatitis...
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Letter
692-694
DOI: 10.17235/reed.2025.11032/2024
Julio César Moreno-Alfonso, Carlos Delgado-Miguel, Sara Hernández Martín, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
While approximately 90% of Meckel's diverticula are asymptomatic, they can manifest with a wide spectrum of complications with a mortality rate of 0.001%. The differential diagnosis is broad, with appendicitis...
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Letter
694-695
DOI: 10.17235/reed.2025.11073/2025
Miguel Fraile López, Álvaro Cobas Bravo, Pedro Luis Fernández Gil, María Moris Felgueroso, Juan Carlos Rodríguez Duque, María Jesús López Arias, Antonio Cuadrado Lavín, Álvaro Terán Lantarón,
Cricopharyngeal achalasia is a rare esophageal motility disorder characterized by the inability to relax of the cricopharyngeal muscle during swallowing. Peroral endoscopic myotomy (POEM) is a minimally...
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Letter
696-697
DOI: 10.17235/reed.2025.11154/2025
Vitorino M. Santos, Andressa Plaça Tedeschi,
Intestinal polyps have been described in association with chronic schistosomiasis, and must be differentiated from malignant tumors and appropriately managed. This uncommon condition may be very rarely...
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Letter
697-698
DOI: 10.17235/reed.2025.11100/2025
Macarena Torres-Larrubia, Sergio Casiano-Manzano, Zulianni Andreina Jiménez-Colmenárez, Joaquín Domínguez-Humanes, Alberto Masa-Caballero, María Herrador-Paredes, Pilar Mata-Romero, Pablo Solís-Muñoz,
We report the case of a 54-year-old male with localized colonic amyloidosis presenting as rectal bleeding. Initial colonoscopy revealed a neoplastic-appearing lesion in the descending colon, but histopathology...
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Letter
698-699
DOI: 10.17235/reed.2024.10412/2024
María Belén López Moreno, Víctor Jiménez Beltrán, María Antonia Godoy López, Jesús García-Cano,
We present the case of a 29-year-old patient with multiple allergies, mild asthma and rhinoconjunctivitis who reported a history of esophageal impactions after ingestion of solid foods. These episodes...
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Letter
699-701
DOI: 10.17235/reed.2025.11216/2025
Julio César Moreno-Alfonso, Rocío del Campo-Pedrosa, Amit Beher, Ada Molina Caballero, Alberto Pérez Martínez, María Concepción Yárnoz Irazábal,
Eosinophilic esophagitis (EoE) is frequently associated with dysphagia and requires esophagoscopy with biopsies for diagnosis, as no reliable diagnostic biomarkers currently exist. While inflammatory indices...
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Letter
701
DOI: 10.17235/reed.2025.11273/2025
Vitorino M. Santos, Kin Modesto Sugai,
Lymphocytic esophagitis is an uncommon condition characterized by the presence of intraepithelial lymphocytosis and lack of eosinophils in the esophageal biopsy samples. The main clinical manifestations...
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Letter
702-703
DOI: 10.17235/reed.2025.11332/2025
Elena Granda Villanueva, Blanca Mesonero de la Cruz, José Manuel Campos Martín, Leire Irusta Olano, Jacobo Martín Sanz, José Eduardo Villela Ramírez, Clara González Rodríguez, Daniel Muíño Domínguez,
Intestinal amyloidosis is an uncommon form of systemic amyloidosis characterized by the extracellular deposition of misfolded immunoglobulin light chains in the gastrointestinal tract, causing structural...
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Letter
703
DOI: 10.17235/reed.2025.11195/2025
Daniel Ramírez Martínez, María Rodríguez González, Ana Sigüenza Lluis, Ana Sanz Vázquez,
We present the case of a 72-year-old man who, during the evaluation of a pancreatic lesion, was found to a secondary plasmacytoma. This is an unusual presentation among pancreatic lesions and should be...
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Letter
704-705
DOI: 10.17235/reed.2025.11290/2025
Maria Dolors Ramis Estelrich, Willy Denis Sánchez Fernández, Pere Vaquer Grimalt, Sarai Blanco Rodríguez, María García García, María Paz Gómez López, Natalia Chausse Vázquez, Isabel Amengual Antich,
Gastritis is the inflammation of the gastric mucosa, which requires histological confirmation for diagnosis. The most common cause is Helicobacter pylori (HP) infection. We present two cases of gastritis...
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Letter
705-706
DOI: 10.17235/reed.2025.11405/2025
Josefa Mora Vallellano, Francisco Cárdenas Lafuente, Sergio Fernández Espínola, Federico Acosta González, Irene Romero García, Ana Martínez Ruiz, Pablo Sánchez González, Daniel Pineda Tenor,
Achieving the World Health Organization's goals for Hepatitis C Virus (HCV) elimination is challenged by patients who remain untreated or are lost to follow-up. We aimed to develop and assess a data-driven...
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Letter
706
DOI: 10.17235/reed.2025.11476/2025
Faviana Nicolette Soberon Montero, Karen Carlessi Saldaña Mendoza, Luz Campos Loza,
The article by Ikegami et al., published in the Revista Española de Enfermedades Digestivas, explores clinical factors affecting the performance of the intestinal patency capsule (IPC). It identifies negative...
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Letter
707-708
DOI: 10.17235/reed.2024.10773/2024
Julia López de la Cruz,
We present the case of a 57-year-old woman with metastatic colorectal cancer being treated with Bevacizumab and FOLFOX, who came to the emergency department with haematemesis. Gastroscopy showed a duodenal...
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