Year 2020 / Volume 112 / Number 4
Original
The rebleeding rate in patients evaluated for obscure gastrointestinal bleeding after negative small bowel findings by device assisted enteroscopy

262-268

DOI: 10.17235/reed.2020.6833/2019

Catarina Gomes, José María Rubio Mateos, Rolando Taveira Pinho, Ana Ponte, Adélia Rodrigues, Margarita Fosado Gayosso, Pilar Esteban Delgado, João Carlos Silva, Edgar Afecto, João Carvalho,

Abstract
Background: data on the long-term outcome of patients with obscure gastrointestinal bleeding (OGIB) with positive small bowel findings in capsule endoscopy but negative small bowel findings in device-assisted enteroscopy are scarce. Objective: this study aimed to evaluate the rebleeding rate and time to rebleed in patients with no small bowel findings in enteroscopy, after a positive capsule endoscopy in the setting of OGIB. Baseline predictors for rebleeding were assessed. Methods: a retrospective double-center study was performed, including patients with OGIB with positive findings by capsule endoscopy and negative small bowel findings by enteroscopy. Results: thirty-five patients were included. Rebleeding occurred in 40 % of patients during a median follow-up of 27 months. Further evaluation in patients with a rebleed was performed in 85.7 %, leading to a final diagnosis in 78.6 %. The rebleeding rate increased progressively over time, from 17.2 % at one month to 54.4 % at four years. Overt bleeding at the time of the first episode was a predictor of rebleeding (p = 0.03) according to the multivariate analysis. This was 50 % at one year compared with 21.8 % in patients with occult bleeding on admission. Conclusions: in obscure gastrointestinal bleeding, long-term follow-up and further evaluation may be considered after a positive capsule endoscopy. Even if there are no small bowel findings by device-assisted enteroscopy. The rebleeding rate in our study was 40 %, mainly in the presence of an overt bleeding on admission.
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doi: 10.17235/reed.2017.4872/2017
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Gomes C, Rubio Mateos J, Pinho R, Ponte A, Rodrigues A, Fosado Gayosso M, et all. The rebleeding rate in patients evaluated for obscure gastrointestinal bleeding after negative small bowel findings by device assisted enteroscopy. 6833/2019


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Publication history

Received: 18/12/2019

Accepted: 01/03/2020

Online First: 23/03/2020

Published: 07/04/2020

Article revision time: 33 days

Article Online First time: 96 days

Article editing time: 111 days


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