Year 2026 / Volume 118 / Number 1

Editorial
1-4
DOI: 10.17235/reed.2025.11255/2025
Diana Fresneda Cuesta, José Díaz Tasende,
Clinical decision-making in patients with pancreatic neuroendocrine tumors is complex. The absence of effective biomarkers and the reliance on morphological criteria underlying current predictive models...
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Original
4-13
DOI: 10.17235/reed.2025.11496/2025
Joaquín Cabezas, Antonio Aguilera, Federico García García, Raquel Domínguez-Hernández, Araceli Casado Gómez, Nataly Espinoza-Cámac, Miguel Ángel Casado, Javier Crespo, María Jesús Alcaraz Soriano on behalf of Task Force Spanish Group for Comprehensive Hepatitis Diagnosis*,

* Task Force Spanish Group for Comprehensive Hepatitis Diagnosis: María Jesús Alcaraz Soriano, Sonia Algarate Cajo, Roberto Alonso Fernández, Maitane Aranzamendi Zaldumbide, Marta Arias Temprano, Ricardo Manuel Arcay Barral, Ana Arribi Vilela, Teresa Arroyo Serrano, Raquel Baluja Pino, Berta Becerril Carral, Rafael Benito Ruesca, Samuel Bernal Martínez, Miriam Blasco Alberdi, Ana Blázquez Abellán, Teresa Cabezas Fernández, Rainer Campo Ramos, María Eliecer Cano García, Purificación Cantudo Muñoz, Laura Cardeñoso Domingo, Ángel Castaño Nuñez, Encarnación Clavijo Frutos, Rodolfo Copado Carretero, Sandra Cortizo Vidal, Alberto de la Iglesia Salgado, María Jesús del Amor Espín, Alberto Delgado Iribarren, Jose Luis Díaz de Tuesta del Arco, Felícitas Díaz-Flores Estévez, María del Carmen Domínguez Jiménez, Victoria Dominguez-Márquez, José María Eiros Bouza, Victoria Fernández Baca, Felipe Manuel Fernández Cuenca, Isabel Fernández Natal, Gema Fernández Rivas, Fernando Fernández Sánchez, Carolina Freyre Carrillo, Ignacio Gadea Gironés, Juan Carlos Galán Montemayor, Fernando García García, María Victoria García López, Sonsoles Garcinuño Pérez, Carmen Gómez González, Alejandro González Praetorius, María José Gude González, Maria Araceli Hernández Betancor, Juan Carlos Hurtado Negreiros, María Asunción Iborra Bendicho, María Magdalena Lara Pérez, María Josefa López de Goicoechea, María Fátima López Fabal, Jose Luis López Hontangas, María Dolores López Prieto, María del Carmen Lozano Domínguez, María Pilar Luzón García, María Dolores Maciá Romero, Yasmina Martín Martín, Olalla Martinez Macias, Ana Miqueleiz Zapatero, Luz Moldes Suárez, Laura Molina Esteban, Dolores Montero Vega, Natalia Montiel Quezel-Guerraz, Carmen Muñoz Almagro, María Navarro Aguirre, María Dolores Navarro Martínez, María Dolores Ocete Mochón, Valle Odero Bernal, Patricia Ordoñez Barrosa, Nieves Orta Mira, Diego Ortega Larrea, María Pilar Palacián Ruiz, María José Pena López, Ana Belén Pérez Jiménez, J. Alfredo Pérez Rivilla, Elisabeth Prieto Rodriguez, Andrés Quesada, Encarnación Ramirez de Arellano, Ariadna Rando Segura, Gabriel Reina González, Juan Carlos Rodríguez Díaz, Francisco Rodríguez Frías, Manuel Ángel Rodríguez Maresca, Luis Rodríguez Otero, Salud Rodríguez Pallares, María Mercedes Rodríguez Pérez, María Rodríguez Velasco, Susana Sabater Vidal, Ruth Sáez de la Maleta Úbeda, Maria Yolanda Salicio Bermejo, Mónica Sánchez Oñoro, Gemma María Sierra Dorado, Raquel Téllez Pérez, Luis Torres Sopena, Matilde Trigo Daporta, María Isabel Zamora Cintas
Introduction: the comprehensive diagnosis of viral hepatitis is an advance towards its elimination, but not all Spanish hospitals performed this diagnosis in 2022. Our objective was to evaluate the situation...
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Original
14-19
DOI: 10.17235/reed.2025.11393/2025
Raquel Carracedo Montero, María de los Ángeles Cañizares, Sandra Cortizo, Matilde Trigo, Noelia Calvo, María José Gude, Patricia Ordóñez, Luz Moldes, Jorge Julio Cabrera, Noelia Parajó, Sara Pereira, Luis Rodríguez Otero, Antonio Aguilera,
Introduction: chronic hepatitis caused by the hepatitis delta virus is the most severe form of viral hepatitis and carries the greatest risk of complications. The real prevalence of this infection remains...
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Original
20-27
DOI: 10.17235/reed.2025.11376/2025
José Lariño Noia, Yessica Domínguez Novoa, Mónica Otero Iglesias, Martiño Loureiro Veira, Marco Galego Fernández, Alberto Rama Fernández, Daniel de la Iglesia, Julio Iglesias García, Enrique Domínguez Muñoz,
Introduction: incidental cystic pancreatic lesions are increasingly detected in the aging population, with branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) being the most common. This study...
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Review
28-40
DOI: 10.17235/reed.2024.10306/2024
Yin Chen, Meisheng Ding,
Background: Constipation, a widespread global issue, prompted an investigation into the intricate relationship between dietary factors and this condition. This study delves into the association between...
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Digestive Diseases Image
41-42
DOI: 10.17235/reed.2025.11253/2025
Marta Fernández Carrasco, Alejandro Rodríguez Mateu, Samia Hallouch Toutouh, Marta Sánchez Tripiana,
Histoplasmosis is an opportunistic infection originating from endemic regions. Current factors such as immigration and immunosuppression associated with new therapeutic approaches increase the likelihood...
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Digestive Diseases Image
43-45
DOI: 10.17235/reed.2024.10323/2024
Zhanwen Xu, Xiaoping Yin,
A 25-year-old male with tachycardia and right heart enlargement was diagnosed with atrial-ventricular nodal reentrant tachycardia (AVNRT) and successfully treated with radiofrequency ablation. Cardiac...
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Digestive Diseases Image
46-47
DOI: 10.17235/reed.2024.10329/2024
Arturo García Pavía, Alex Akana Ngatia, Jackson Lokili Ebune,
A 7-year-old girl, coming from a rural area in Cameroon, presented to the emergency department with a 3-months history of abdominal pain. Her family also reported vomiting and minimal food intake for two...
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Letter
48-49
DOI: 10.17235/reed.2024.10767/2024
Lidia Campos Gonzaga, Juan Cristóbal Aguilar Martínez, Teresa Castro Tablada,
We present the case of a 72-year-old male who was admitted to the Digestive Unit due to an increase in the number of stools (>40 per day) and a change in stool characteristics. Initially a neoplastic lesion...
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Letter
49-50
DOI: 10.17235/reed.2024.10813/2024
Youhong Cao, Chen Yuan,
Schistosoma japonicum, which has been endemic for a long time, associated colon abnormality has also been sporadically reported. The majority of patients with Schistosomiasis japonicum infected may mainly...
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Letter
50-51
DOI: 10.17235/reed.2024.10837/2024
Jiaju Liu, Zhiyong Fang,
A 52-year-old male was diagnosed with primary liver cancer in June 2021 after experiencing abdominal pain and bloating. He had previously undergone resection for a Merkel cell tumor in March 2021, with...
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Letter
51-52
DOI: 10.17235/reed.2024.10841/2024
Yuko Tasato, Yoshiki Chinen, Kyoko Arakaki, Mayumi Shiroma, Masaru Miyazato, Noriya Nakachi, Ryosaku Tomiyama, Akira Hokama,
An 82-year-old woman presented with painless hematochezia. Colonoscopy revealed a submucosal tumor-like mass in the cecum. The appendiceal orifice was identified in the center of the prominence, showing...
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Letter
52-53
DOI: 10.17235/reed.2024.10849/2024
Carlos Alventosa-Mateu, Mercedes Latorre Sánchez, Inmaculada Castelló Miralles, Benjamín Climent Díaz, Juan José Urquijo Ponce, Moisés Diago Madrid,
This pilot study evaluates the presence of potential unrecognized steatotic liver disease with moderate alcohol consumption (MetALD) in patients diagnosed with metabolic dysfunction-associated steatotic...
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Letter
53-54
DOI: 10.17235/reed.2024.10810/2024
Eduard Espinet Coll, Javier Nebreda Durán, Román Turró Arau, Ramón Abad Belando, Fernando Saenger, Óscar Núñez Martínez, Manoel Galvao Neto,
We present the Clinical Trial results of the first Spanish intragastric balloon manufactured: the Stella® balloon (SwanMedical, Barcelona). As a peculiarity, it has a double lumen in the introducer system....
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Letter
55-56
DOI: 10.17235/reed.2024.10868/2024
Ruihan Zou, Xiaohan Jiang, Min Wang, Yao Wang, Lili Zhao, Zhining Fan,
Chemical burns of the rectum are so rare that there are few cases reported about this situation. In fact, chemical burns of the rectum can cause severe serious consequence, such as bleeding, perforation...
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Letter
56-57
DOI: 10.17235/reed.2024.10853/2024
Elena Pablo-Martín, Laura Corvo-Félix, Marta Rodríguez González, Andrea Beatriz Jiménez Pérez, Luis Figuero-Pérez, María Luisa Pérez García, Emilio Fonseca-Sánchez,
We present the case of a 27-year-old man, with no previous diseases, who was referred to the Department of Otorhinolaryngology in May 2023 for a 2-cm right submandibular lymphadenopathy of two month’s...
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Letter
57-58
DOI: 10.17235/reed.2024.10862/2024
Carolina Broco Fernández, Ana Belen Dominguez Carbajo, Santiago Vivas Alegre, Verónica Patiño Delgadillo, Laura Alcoba Vega, Francisco Jorquera Plaza,
Plummer-Vinson syndrome (PVS) is a rare disorder characterized by a triad of iron-deficiency anemia, cervical dysphagia, and post-cricoid esophageal webs. The exact relationship between anemia and web...
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Letter
58-59
DOI: 10.17235/reed.2024.10829/2024
Laura Cudero Quintana, Álvaro Hidalgo Romero, Ana Teijo Quintáns, José Benjamín Díaz Tasende, Inmaculada Fernández Vázquez,
Early diagnosis of abdominal actinomycosis is challenging due to its atypical presentation as an abdominal mass, which may mimic colon cancer. Initial clinical suspicion is crucial to guide treatment and...
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Letter
59-60
DOI: 10.17235/reed.2024.10880/2024
Chen Yuan, Fang Wang, Youhong Cao,
Endoscopic fragmentation or removement of gastric bezoar is the simplest, most cost-effective approach, while the traditional endoscopic device include foreign body forceps, polypectomy snare, laser lithotripsy,...
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Letter
60-62
DOI: 10.17235/reed.2024.10856/2024
Yekai Zhou, Xiaorong Chen, Jie Li, Fang Luo,
We present a rare case of ruptured pancreatic carcinosarcoma in a 56-year-old male who underwent radical surgery and adjuvant chemotherapy. Despite the typical poor prognosis associated with this aggressive...
Reader rating:
Letter
62-63
DOI: 10.17235/reed.2024.10833/2024
Andrés Castañeda, Marta Álvarez García, Cristina Serrano del Castillo, Raquel Téllez Pérez, Ana Pilar Lanzarote Vargas, María José Romero Valle, Lonore Hurtado de Mendoza, Sergio Farrais Villalba,
We present the clinical case of a 39-year-old woman with a medical history of juvenile idiopathic arthritis and uveitis, evaluated for abdominal pain and distension, difficulty gaining weight, and diarrhea....
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Letter
63-64
DOI: 10.17235/reed.2024.10791/2024
María Pascual Lorén, Ana Martín-Adrados, Rosa María González Cervera, Jorge Martínez Pérez, Ana Isabel Quintero García, Rosa Ana Muñoz Codoceo,
Celiac disease (CD) is an autoimmune disorder triggered by gluten in genetically predisposed individuals, often diagnosed by detecting anti-tTG2 antibodies. First-degree relatives of CD patients are at...
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Letter
64-65
DOI: 10.17235/reed.2025.11499/2025
Juan Enrique Domínguez Muñoz, José Lariño Noia, Yessica Domínguez Novoa, Julio Iglesias-García,
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely prescribed for type 2 diabetes mellitus (T2DM) and weight management. These medications mimic the effects of the intestinal hormone GLP-1,...
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