Year 2010 / Volume 102 / Number 10
Original
Chronic hepatitis C treatment in a cystic fibrosis patient in the pulmonary pre-transplant stage

pp. 587-590

L. Adán Merino, A. Olveira Martín1 C. Prados, F. Gea Rodríguez, P. Castillo Grau, E. Martín Arranz, J. C. Sáenz y J. M. Segura Cabral

Abstract
The standard treatment of chronic hepatitis C, pegylated interferon and ribavirin (pegI/R), has many limitations in both effectiveness and secondary effects, which makes it unsuitable or even contraindicated for some patients. In hepatitis C virus-infected cystic fibrosis patients this treatment could increase respiratory infections
with subsequent pulmonary function deterioration. On the contrary, hepatitis C virus (HCV) infection may make lung transplant (LT) unfeasible. We present the case of a cystic fibrosisyoung
man diagnosed with HCV infection during LT assessment who was treated with pegI/R. In spite of the lung function worsening and respiratory infections, he managed to complete treatment
and even sustained virological response (SVR). At present he is on LT waiting list.
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L. Adán Merino, A. Olveira Martín1 C. Prados, F. Gea Rodríguez, P. Castillo Grau, E. Martín Arranz, J. C. Sáenz y J. M. Segura Cabral. Chronic hepatitis C treatment in a cystic fibrosis patient in the pulmonary pre-transplant stage. 587-590


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