Year 2019 / Volume 111 / Number 2
Letter
Minute adenocarcinoma on Barrett's esophagus: the importance of directed biopsy sampling

164

DOI: 10.17235/reed.2018.5579/2018

Violeta María Sastre Lozano, José Jaime Vicente López, Senador Morán Sánchez,

Abstract
Patients with Barrett's esophagus (BE) have a risk of esophageal cancer thirty times higher than the general population. The grade of dysplasia must be established during endoscopic follow-up. The effectiveness of endoscopic surveillance programs for the diagnosis of advanced esophageal adenocarcinoma has been questioned. Several techniques are available for the early identification of high-grade dysplasia and biopsy sampling in all four quadrants every 2 cm is the most common procedure. However, accurate protocol compliance is challenging for some conditions, including long BE, due to the excessive number of biopsies that may be required.
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References
1. Arroyo-Martínez Q, Rodríguez-Téllez M, García-Escudero A et al. Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain. A unicentric study. Rev Esp Enferm Dig. 2016;108(10):609-617
2. Shaheen NJ, Falk GW, Iyer PG, et al. ACG Clinical Guideline: Diagnosis and Management of Barrett's Esophagus. Am J Gastroenterol 2016; 111:30.
3. Vennalaganti PR, et al. Increased detection of Barrett’s esophagus–associated neoplasia using wide-area trans-epithelial sampling: a multicenter, prospective, randomized trial. Gastrointestinal Endoscopy 2018; 87(2):348-355.
4. Espinel J, Pinedo E, Rascarachi G. Endoscopic Mucosal Resection with a multiband ligator for the treatment of Barrett´s high-grade dysplasia and early gastric cancer. Rev Esp Enf Dig 2009. 101(6). 403-407.
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Sastre Lozano V, Vicente López J, Morán Sánchez S. Minute adenocarcinoma on Barrett's esophagus: the importance of directed biopsy sampling . 5579/2018


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Publication history

Received: 06/03/2018

Accepted: 04/07/2018

Online First: 15/10/2018

Published: 01/02/2019

Article Online First time: 223 days

Article editing time: 332 days


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