Year 2021 / Volume 113 / Number 8
Original
Clinical study of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen in the treatment of advanced esophageal cancer

576-579

DOI: 10.17235/reed.2020.7377/2020

Qi-zhou Zhang, Guo-liang Li, Jian-biao Shang, Yi-min Ren, Jian-li Xie,

Abstract
Objective: this study aimed to investigate the clinical efficacy and feasibility of the treatment of advanced esophageal cancer with a combination of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen. Methods: forty-five patients with advanced esophageal cancer were enrolled and were randomly divided into two groups: a treatment group and a control group. Patients in the treatment group were treated with a 125I particle-integrated esophageal covered stent and hyperbaric oxygen, while patients in the control group were treated with a 125I particle-integrated esophageal covered stent. The clinical effects and long-term survival time of the two groups were observed. Results: in the treatment group, the complete remission (CR) rate and partial remission (PR) rate of local lesions were 19.2 % and 61.5 %, respectively, and the total effective rate was 80.7 %. In the control group, the CR rate and PR rate of local lesions were 10.5 % and 52.6 %, respectively, and the total effective rate was 63.1 %. The total effective rate was higher in the treatment group than in the control group, which was statistically significant (p < 0.05). Conclusion: the combination of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen shows a good short- and long-term efficacy in the treatment of advanced esophageal cancer.
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Zhang Q, Li G, Shang J, Ren Y, Xie J. Clinical study of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen in the treatment of advanced esophageal cancer. 7377/2020


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Publication history

Received: 28/06/2020

Accepted: 21/09/2020

Online First: 02/12/2020

Published: 28/07/2021

Article revision time: 77 days

Article Online First time: 157 days

Article editing time: 395 days


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